Hallmarks of Parkinson’s Disease

doi:10.3390/books978-3-0365-5016-9

Download Url(s)

https://mdpi.com/books/pdfview/book/5964

Contributor(s)

Alves Da Costa, Cristine (editor)

Language

English

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Abstract

This book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson’s disease, including ER stress, mitophagy and alpha-synuclein-linked pathology.

URI

https://directory.doabooks.org/handle/20.500.12854/97459

Keywords

Parkinson’s disease; unfolded protein response; reticulum endoplasmic; genetics; alpha-synuclein; prion-like spreading; cell-to-cell transfer; neurodegeneration; mitochondrial dysfunction; PINK1; neurons; astrocytes; microglia; α-synuclein; exocytosis; lipids; membranes; Parkinson disease; SNARE complex; synapse; vesicle fusion; therapeutic target; protein quality control; mitochondrial quality control; ubiquitin; alpha-syn; mitophagy; Parkin; mito-Keima; mito-QC; mito-SRAI