Marine Drug Research in China: Selected Papers from the 15-NASMD Conference

doi:10.3390/books978-3-0365-4570-7

Download Url(s)

https://mdpi.com/books/pdfview/book/5911

Contributor(s)

Zhou, Xuefeng (editor)

Luo, Xiaowei (editor)

Liu, Yonghong (editor)

Language

English

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Abstract

The Book covers this whole field, from the discovery of structurally new and bioactive natural products (including biomacromolecules), from marine macro-/micro-organisms, to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, both in vitro and in vivo, along with the synthesis and/or structural optimization of marine-derived lead compounds and their structure–activity relationships. Taken together, this Special Issue reprint not only provides inspiration for the discovery of marine-derived novel bioactive compounds, but also sheds light on the further research and development of marine candidate drugs.

URI

https://directory.doabooks.org/handle/20.500.12854/92038

Keywords

Antarctic krill (Euphausia superba); peptide; antioxidant activity; stability; oyster; plasma; peptidome; antimicrobial peptides; cytotoxicity; actinomycete; piericidins; absolute configuration; Pestalotiopsis heterocornis; heterocornols; anti-inflammatory activity; sponge-derived fungus; sclerotides; lipodepsipeptide; Aspergillus sclerotiorum; nasopharyngeal carcinoma; AChE inhibitory; vascular endothelial cell; flavonoid; oxidized low-density lipoprotein; Nrf2; apoptosis; butyrolactone I; food allergy; metabolism; pharmacokinetics; actinomycin X2; microbial pigments; dyeing; silk; antibacterial properties; PD-L1; virtual screening; pharmacophore modeling; ADME; molecular dynamics; xanthones; ascidian-derived fungus; Diaporthe sp.; anti-glioma activity; antiaging; Sonneratia apetala; signaling pathway; Caenorhabditis elegans; mutants; coral-derived fungi; Aspergillus hiratsukae; meroterpenoids; antibacterial activity; cytotoxic activity; deep-sea-derived fungus; Aspergillus puniceus; isoquinoline alkaloid; protein tyrosine phosphatase inhibitor; antibacterial; Aspergillus sp.; geodin; semisynthesize; insecticidal activity; Arca inflata; antitumor peptide; MAPK signaling; calmodulin; colorectal cancer; methicillin-resistant Staphylococcus aureus; actinomycin D; Streptomyces parvulus; mechanism; mangrove endophytic Pestalotiopsis; Sdy-1; antitumor activity; Wnt signaling; β-catenin; eremophilane sesquiterpenoids; mangrove-derived fungus; Penicillium sp.; Oceanapia; sponge; secondary metabolites; biological activities; drug design; anticancer; cyclic pentapeptide; galaxamide analogues; skipjack tuna (Katsuwonus pelamis) muscle; angiotensin-I-converting enzyme (ACE) peptide; molecular docking; nitric oxide (NO); endothelin-1 (ET-1); Trichoderma longibrachiatum; sesquiterpene glycoside; antimicrobial activity; marine fungi; Aspergillus unguis; depsides; depsidones; osteoclast differentiation; soft-coral-derived fungus; pyranodipyran derivatives; tyrosyl DNA phosphodiesterase 1 inhibitory activities; fluorescent properties; butenolides; enantiomers; Aspergillus terreus; pancreatic lipase; NAFLD; fucoxanthin; adenosine monophosphate-activated protein kinase (AMPK); nuclear factor erythroid-2-related factor 2-mediated (Nrf2); Toll-like receptor 4-mediated (TLR4); Aspergillus flavipes HN4-13; emodin; macroporous resin XAD-16; adsorption kinetics and isotherms; enrichment; tetramic acid derivatives; deep-sea fungus; clavipitacae; Lecanicillium fusisporum; chronic kidney disease; fucoidan; cognitive dysfunction; neuroinflammation; oxidative stress; GSK3β-Nrf2-HO-1 signaling; microglial polarization; deep-sea actinomycetes; aromatic acids; oximes; antihyperlipidemic; phycocyanin; microbiota; transcriptome; IL-17 pathway; Hahella; prodiginine; chejuenlide; genome mining; LC-MS/MS; CDK4/6; marine compounds; pharmacophore construction; ADMET; mm-pbsa