Intervertebral Disc Regeneration
Gantenbein, Benjamin (editor)
This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.
Keywordshyaluronic acid; disc repair; annulus fibrosus repair; biomaterials; inflammatory biomarkers and signalling pathways; nasal chondrocytes; disc degeneration; inflammation; microenvironment; nucleus pulposus; cell; spine; intervertebral disc; renin–angiotensin system; degeneration; regeneration; intervertebral disc (IVD); stem cell; scaffolds; tissue engineering; test method; dynamic testing; in vitro; (lumbar) disc herniation; physiological activities; regenerative approaches; nucleus pulposus progenitor cells; cryopreservation; Tie2; spheroid colony; EZSPHERE; CryoStor 10; growth factors; differentiation; mesenchymal stromal cell; growth factor; Wnt; differentiation factor; chondrogenesis; cell therapy; progenitor cells; biomechanics; lumbar disc herniation; GDF5; GDF6; TGFβ; nucleus pulposus progenitor cells (NPPC); losartanon
Webshop linkhttps://mdpi.com/books/pdfview ...
Publication date and placeBasel, 2022
History of engineering & technology