Application of LC-MS/MS in the Mycotoxins Studies

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https://mdpi.com/books/pdfview/book/2382Contributor(s)
Gámiz-Gracia, Laura (editor)
García-Campaña, Ana M. (editor)
Arroyo-Manzanares, Natalia (editor)
Language
EnglishAbstract
Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids.
Keywords
cereals; mycotoxigenic fungi; phylogeny; deoxynivalenol; zearalenone; Sub-Saharan Africa; aflatoxins; mycotoxins; total diet study; food contaminants; LC-MS/MS; Alternaria toxins; grape; modified QuEChERS; UHPLC-MS/MS; n/a; traditional sorghum malts; Aspergillus; LC/MS/MS; Biomarkers; exposure; LC-HRMS; pig; broiler chicken; multi-mycotoxin; stability; malting; brewing; beer; feed; liquid chromatography; fluorescence detection; mass spectrometry; solid-liquid extraction; co-occurrence; metabolism; high-resolution mass spectrometry (HRMS); microsomal incubation; glucuronidation; human; biomonitoring; UPLC-MS/MS; rumen fluid; maize silage; matrix-matched; moniliformin; lanthanide complexes; LC-UV; collaborative study; isotopic dilution; compliance; infant food; emergent mycotoxins; urine; dispersive solid-phase extraction; magnetic carbon nanotube composite; pesticides; Q-Exactive Orbitrap; CBD capsule; nutraceutical; Fusarium; maize; masked mycotoxins; agricultural regions; South Africa; Mycotoxins; exposure assessment; Algeria; mixed feed rations; QuEChERS; dispersive solid phase extraction; high-resolution mass spectrometry; data independent SWATHWebshop link
https://mdpi.com/books/pdfview ...ISBN
9783039362066, 9783039362073Publisher website
www.mdpi.com/booksPublication date and place
Basel, Switzerland, 2020Classification
Medicine and Nursing