Chapter 15 Brain Tumors and the Lynch Syndrome

Peltomäki, Päivi; Gylling, Annette

doi:10.5772/21293

Download Url(s)

https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf
---
https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf
---
https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf
---
https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf
---
https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf

Author(s)

Peltomäki, Päivi

Gylling, Annette

Collection

European Research Council (ERC); EU collection

Language

English

Show full item record

Abstract

Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003).

Book

Management of CNS Tumors

URI

https://directory.doabooks.org/handle/20.500.12854/37172

Keywords

brain tumors; lynch syndrome; brain tumors; lynch syndrome; Colorectal cancer; DNA methylation; DNA mismatch repair; Gene; Glioblastoma; Glioma; Hereditary nonpolyposis colorectal cancer; Mutation; Neoplasm