Hypothalamic Regulation of Obesity

doi:10.3390/books978-3-0365-7392-2

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https://mdpi.com/books/pdfview/book/7203

Contributor(s)

Rodríguez-Rodríguez, Rosalía (editor)

Miralpeix, Cristina (editor)

Language

English

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Abstract

The manuscripts published in this reprint provide new insights into the hypothalamic neuronal and non-neuronal pathways involved in the pathophysiology and development of obesity and related diseases such as diabetes. Via four original papers, six review manuscripts, and one perspective, this reprint will substantially contribute to the identification of novel therapeutic targets in the hypothalamus and novel approaches to combatting the progression of human obesity.

URI

https://directory.doabooks.org/handle/20.500.12854/100110

Keywords

SIRT1; SIRT6; energy balance; food intake; body weight; adiposity; type 2 diabetes; obesity; adiponectin; astrocyte; energy metabolism; hypothalamus; glycolysis; metabolic diseases; microglia; gliosis; high-fat diet; transcriptomic; sex difference; estradiol; nociceptin/orphanin FQ; pituitary adenylate cyclase-activating polypeptide; fasting; AGF; leptin; POMC neuron; neurosecretory protein GL; neuropeptide; glucose homeostasis; insulin sensitivity; microglia–neuron communication; metabolism; Alzheimer’s disease; 5xFAD; insulin signaling; energy expenditure; neuroinflammation; microbiota; gut–brain axis; nutrient sensing; food intake and obesity; astrocytes; neurons; SF1 neurons; ventromedial hypothalamus nucleus; diabetes; energy homeostasis; n/a