Advanced Blood-Brain Barrier Drug Delivery
dc.contributor.editor | Pardridge, William M. | |
dc.date.accessioned | 2023-02-02T16:44:46Z | |
dc.date.available | 2023-02-02T16:44:46Z | |
dc.date.issued | 2023 | |
dc.identifier | ONIX_20230202_9783036564173_130 | |
dc.identifier.uri | https://directory.doabooks.org/handle/20.500.12854/96729 | |
dc.description.abstract | Advanced Blood-Brain Barrier Drug Delivery is a reprint with a summary editorial, followed by 16 chapters that cover five areas of brain drug delivery, including receptor-mediated transport (RMT), carrier-mediated transport (CMT), active efflux transport (AET), Trojan horse lipid nanoparticles (LNP), and in vivo methods for measurement of drug transport across the blood–brain barrier (BBB). | |
dc.language | English | |
dc.subject.classification | thema EDItEUR::M Medicine and Nursing | en_US |
dc.subject.classification | thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology | en_US |
dc.subject.other | blood–brain barrier (BBB) | |
dc.subject.other | brain drug delivery | |
dc.subject.other | prodrugs | |
dc.subject.other | solute carriers (SLCs) | |
dc.subject.other | lysosomal storage disease | |
dc.subject.other | neuronopathic mucopolysaccharidosis | |
dc.subject.other | blood–brain barrier | |
dc.subject.other | neurodegeneration | |
dc.subject.other | enzyme replacement therapy | |
dc.subject.other | receptor-mediated transcytosis | |
dc.subject.other | transferrin receptor | |
dc.subject.other | insulin receptor | |
dc.subject.other | endothelium | |
dc.subject.other | receptor-mediated transport | |
dc.subject.other | carrier-mediated transport | |
dc.subject.other | genetic engineering | |
dc.subject.other | IgG fusion proteins | |
dc.subject.other | nanoparticles | |
dc.subject.other | liposomes | |
dc.subject.other | TrkB | |
dc.subject.other | agonist antibody | |
dc.subject.other | variable new antigen receptor (VNAR) | |
dc.subject.other | neuroprotection | |
dc.subject.other | transferrin receptor 1 (TfR1) | |
dc.subject.other | blood-brain barrier (BBB) | |
dc.subject.other | 6-OHDA | |
dc.subject.other | Parkinson’s disease | |
dc.subject.other | bispecific antibody | |
dc.subject.other | alpha-synuclein (αSYN) | |
dc.subject.other | Parkinson’s disease (PD) | |
dc.subject.other | immunotherapy | |
dc.subject.other | monoclonal antibody | |
dc.subject.other | transferrin receptor (TfR) | |
dc.subject.other | receptor-mediated transcytosis (RMT) | |
dc.subject.other | single domains antibody | |
dc.subject.other | IGF1R | |
dc.subject.other | neurotensin | |
dc.subject.other | protein-based therapy | |
dc.subject.other | lysosomal storage disorders | |
dc.subject.other | fusion proteins | |
dc.subject.other | Alzheimer’s disease | |
dc.subject.other | neurotrophic factors | |
dc.subject.other | decoy receptors | |
dc.subject.other | ATP-binding cassette transporters | |
dc.subject.other | drug delivery | |
dc.subject.other | ischemic stroke | |
dc.subject.other | SLC transporters | |
dc.subject.other | lipid nanoparticle | |
dc.subject.other | ssPalm | |
dc.subject.other | mRNA transfection | |
dc.subject.other | hCMEC/D3 cells | |
dc.subject.other | cell toxicity | |
dc.subject.other | SWATH-MS | |
dc.subject.other | translation | |
dc.subject.other | chaperonin-containing TCP-1 | |
dc.subject.other | proton-coupled organic cation antiporter | |
dc.subject.other | photo-affinity labeling | |
dc.subject.other | proteomics | |
dc.subject.other | SWATH-MS (sequential window acquisition of all theoretical-mass spectra) | |
dc.subject.other | pharmacokinetics | |
dc.subject.other | compartmental models | |
dc.subject.other | physiologically based PK models | |
dc.subject.other | blood-brain barrier | |
dc.subject.other | antibody | |
dc.subject.other | cavernous sinus | |
dc.subject.other | BBB–peptide shuttle | |
dc.subject.other | brain delivery | |
dc.subject.other | solute carrier (SLC) transporters | |
dc.subject.other | amyotrophic lateral sclerosis (ALS) | |
dc.subject.other | NSC-34 cell lines | |
dc.subject.other | taurine transporter (Taut) | |
dc.subject.other | large amino acid transporter 1 (LAT1) | |
dc.subject.other | monocarboxylate transporters (MCTs) | |
dc.subject.other | organic cation transporters (OCTNs) | |
dc.subject.other | choline transporter-like protein-1 (CTL1) | |
dc.subject.other | TNF-α inhibitor | |
dc.subject.other | molecular Trojan horse | |
dc.subject.other | endosomal | |
dc.subject.other | liposome | |
dc.subject.other | nanoparticle | |
dc.subject.other | targeting | |
dc.subject.other | transferrin | |
dc.subject.other | n/a | |
dc.title | Advanced Blood-Brain Barrier Drug Delivery | |
dc.type | book | |
oapen.identifier.doi | 10.3390/books978-3-0365-6416-6 | |
oapen.relation.isPublishedBy | 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 | |
oapen.relation.isbn | 9783036564173 | |
oapen.relation.isbn | 9783036564166 | |
oapen.pages | 496 | |
oapen.place.publication | Basel |
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