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dc.contributor.editorButler, Merlin G.
dc.date.accessioned2022-05-06T11:23:38Z
dc.date.available2022-05-06T11:23:38Z
dc.date.issued2022
dc.identifierONIX_20220506_9783036536095_102
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/81036
dc.description.abstractThe Identification of the Genetic Components of Autism Spectrum Disorders 2019 will serve as a resource for laboratory and clinical scientists as well as translational-based researchers, primary healthcare providers or physicians, psychologists/psychiatrists, neurologists, developmental pediatricians, clinical geneticists, and other healthcare providers, teachers, caregivers and students involved in autism spectrum disorders (ASD) with the goal to translate information directly to the clinic, education and home setting. Other professionals, students and families might find this textbook of value based on better awareness, causes and understanding of genetic components leading to autism and open avenues for treatment. Genetics play a role with up to 90% of autism, with over 800 currently recognized genes contributing to causes, clinical presentation, treatment, and counseling of family members. This textbook includes 13 chapters divided into three sections (clinical, genetics, other) written by experts in the field dedicated to research and clinical care, description, treatment and generating relevant reviews for ASD and related disorders impacting gene expression, profiling, and pathways. Identification of potential risk factors will be discussed, including obesity, microbiota, malignancy, and the immune system, as well as their direct or indirect contribution to ASD treatment and causation.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)en_US
dc.subject.otherautism spectrum disorders (ASD)
dc.subject.othercancer
dc.subject.otheroverlapping genes and gene profiling
dc.subject.othersuper-pathways
dc.subject.otherphenotypes and diseases
dc.subject.othermolecular functions and processes
dc.subject.other15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome
dc.subject.otherimprinting
dc.subject.otherparent-of-origin effects
dc.subject.otherphenotype-genotype correlation
dc.subject.otherautism
dc.subject.otherdevelopmental delays
dc.subject.othermotor delays
dc.subject.othermicrobiome
dc.subject.othergut
dc.subject.otherProSAP2
dc.subject.otherPhelan McDermid Syndrome
dc.subject.othergut–brain interaction
dc.subject.otherleaky gut
dc.subject.otherIL-6
dc.subject.otherSHANK
dc.subject.othercollapsin response mediator protein 4
dc.subject.otherautism spectrum disorder
dc.subject.otherneurodevelopmental disorder
dc.subject.otherwhole-exome sequencing
dc.subject.otheranimal model
dc.subject.othersex different phenotypes
dc.subject.other15q11.2 BP1–BP2 microdeletion (Burnside–Butler syndrome)
dc.subject.otherNIPA1
dc.subject.otherNIPA2
dc.subject.otherCYFIP1
dc.subject.otherTUBGCP5 genes
dc.subject.otherPrader–Willi and Angelman syndromes
dc.subject.othermagnesium transporters and supplementation
dc.subject.otherpotential treatment options
dc.subject.otherintellectual disability
dc.subject.otherAMPA receptors
dc.subject.otherNMDA receptors
dc.subject.otherguanine nucleotide exchange factor
dc.subject.othersynaptic plasticity
dc.subject.otherAutism spectrum disorder
dc.subject.otherASD
dc.subject.otherObesity
dc.subject.otherOverweight
dc.subject.otherBody mass index
dc.subject.otherBMI
dc.subject.otherautism candidate genes
dc.subject.othersynaptotagmin-like protein 4 (SYTL4)
dc.subject.othertransmembrane protein 187 (TMEM187)
dc.subject.otherSYTL4-protein structure
dc.subject.otherSTRING-protein-protein interaction
dc.subject.otherexpression profile
dc.subject.othermicroRNA- interactions
dc.subject.otherautism spectrum disorders
dc.subject.otherbiological networks
dc.subject.othergenomics
dc.subject.othermulti-omics
dc.subject.othernetwork diffusion
dc.subject.otherdata integration
dc.subject.othergenetics
dc.subject.otherquantitative traits
dc.subject.otherstratification by trait severity
dc.subject.otherheterogeneity reduction
dc.subject.othercase-control association analysis
dc.subject.otherfragile X syndrome
dc.subject.otherRNA toxicity
dc.subject.otherDNA methylation
dc.subject.othermosaicism
dc.subject.otherpediatrics
dc.subject.otherMS-QMA
dc.subject.otherAmplideX
dc.subject.othercytokine
dc.subject.othermonocyte
dc.subject.otherβ-glucan
dc.subject.otherT cell cytokine
dc.subject.othertrained immunity
dc.subject.othermaternal immune activation
dc.subject.otherepigenetics
dc.subject.othermice
dc.subject.otherpostnatal VPA injection
dc.subject.otherSAM
dc.subject.othergene expression
dc.subject.othernanostring
dc.titleIdentification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-3610-1
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036536095
oapen.relation.isbn9783036536101
oapen.pages256
oapen.place.publicationBasel


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