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Insulin-Like Growth Factors in Development, Cancers and Aging

dc.contributor.editorWerner, Haim
dc.date.accessioned2022-01-11T13:33:18Z
dc.date.available2022-01-11T13:33:18Z
dc.date.issued2021
dc.identifierONIX_20220111_9783036507705_222
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/76486
dc.description.abstractThis Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology. The present Special Issue highlights some of the most important topics in the broad area of IGF research, including the role of IGF1 in aging and longevity, attempts to target the IGF1 axis in oncology, the role of IGF-binding proteins, structural aspects of IGF-II, etc. We trust that this assembly of articles will be of great help to students, basic researchers and practitioners.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.otherIGF-I
dc.subject.otherIGF-II
dc.subject.otherinsulin
dc.subject.otherIGF-IR
dc.subject.otherIRs
dc.subject.othertyrosine kinase receptor
dc.subject.otherGPCRs
dc.subject.otherhybrids
dc.subject.otherphosphorylation
dc.subject.otherG-proteins
dc.subject.otherβ-arrestins
dc.subject.otherfunctional RTK/GPCR hybrid
dc.subject.othernuclear translocation
dc.subject.otherIGF-I receptor
dc.subject.othersignaling
dc.subject.othertargeted therapeutics
dc.subject.otherIGF-Trap
dc.subject.otherIGF system
dc.subject.otherIGFBP-3
dc.subject.otherIGFBP-3R
dc.subject.otherTMEM219
dc.subject.otheranti-tumor
dc.subject.otheranti-metastatic
dc.subject.otheragonists
dc.subject.othermAb therapy
dc.subject.otherIGF-1
dc.subject.otherIGFBP-1
dc.subject.otherolder adults
dc.subject.otherlongevity
dc.subject.otherhealth-span
dc.subject.otherage-related disease
dc.subject.othercognitive impairment
dc.subject.otherdiabetes
dc.subject.othermitochondria
dc.subject.othergrowth hormone
dc.subject.otherinsulin-like growth factor-1
dc.subject.otheraging
dc.subject.otheroxidative stress
dc.subject.othersenescence
dc.subject.otherlongitudinal study
dc.subject.otherIGFBP
dc.subject.othermouse models
dc.subject.otherskeletal muscle
dc.subject.otherMSCs
dc.subject.othermyogenesis
dc.subject.otherglucose regulated protein (GRP) 94
dc.subject.otherinsulin-like growth factor
dc.subject.otherobligate chaperone
dc.subject.otherhypertrophy
dc.subject.otheratrophy
dc.subject.othercachexia
dc.subject.othermuscle regeneration
dc.subject.otherautophagy
dc.subject.otherIGF-1R
dc.subject.otherinsulin receptor
dc.subject.otherIR-A
dc.subject.otherstructural studies
dc.subject.otherreceptor activation
dc.subject.othern/a
dc.titleInsulin-Like Growth Factors in Development, Cancers and Aging
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-0771-2
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036507705
oapen.relation.isbn9783036507712
oapen.pages196
oapen.place.publicationBasel, Switzerland


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