Killing Cancer : Discovery and Selection of New Target Molecules

doi:10.3390/books978-3-03943-441-1

dc.contributor.editor	Kallunki, Tuula
dc.date.accessioned	2021-05-01T15:45:58Z
dc.date.available	2021-05-01T15:45:58Z
dc.date.issued	2020
dc.identifier	ONIX_20210501_9783039434404_1037
dc.identifier.uri	https://directory.doabooks.org/handle/20.500.12854/69291
dc.description.abstract	Despite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million by 2030. There is clearly a need for not only more research but also more innovative and out of the mainstream scientific ideas to discover and develop even better cancer treatments. This book presents the collective works published in the recent Special Issue entitled “Killing Cancer: Discovery and Selection of New Target Molecules”. These articles comprise a selection of studies, ideas, and opinions that aim to facilitate knowledge, thoughts, and discussion about which biological and molecular mechanisms in cancer we should target and how we should target them.
dc.language	English
dc.subject.classification	thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general	en_US
dc.subject.classification	thema EDItEUR::P Mathematics and Science::PS Biology, life sciences	en_US
dc.subject.other	ferlin
dc.subject.other	myoferlin
dc.subject.other	dysferlin
dc.subject.other	otoferlin
dc.subject.other	C2 domain
dc.subject.other	plasma membrane
dc.subject.other	sulconazole
dc.subject.other	NF-κB
dc.subject.other	IL-8
dc.subject.other	mammosphere
dc.subject.other	breast cancer stem cells
dc.subject.other	AF1Q
dc.subject.other	MLLT11
dc.subject.other	WNT
dc.subject.other	STAT
dc.subject.other	esophageal cancer
dc.subject.other	prognosis
dc.subject.other	mTORC1
dc.subject.other	mTORC2
dc.subject.other	metabolism
dc.subject.other	rapalogs
dc.subject.other	mTOR inhibitors
dc.subject.other	cancer metabolism
dc.subject.other	mTOR in immunotherapy
dc.subject.other	nutrient metabolism
dc.subject.other	kinase inhibitors
dc.subject.other	mTOR signaling
dc.subject.other	MAPK kinase
dc.subject.other	ERK1
dc.subject.other	ERK2
dc.subject.other	CD domain
dc.subject.other	Rolled
dc.subject.other	SCH772984
dc.subject.other	VRT-11E
dc.subject.other	sevenmaker
dc.subject.other	cancer therapy
dc.subject.other	EMT
dc.subject.other	lysosome
dc.subject.other	lysosome-mediated invasion
dc.subject.other	MZF1
dc.subject.other	phosphorylation
dc.subject.other	PAK4
dc.subject.other	SUMOylation
dc.subject.other	transcription factor
dc.subject.other	zinc finger
dc.subject.other	glucocorticoids
dc.subject.other	3D growth
dc.subject.other	nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB)
dc.subject.other	epithelial–mesenchymal transition
dc.subject.other	anoikis
dc.subject.other	proliferation
dc.subject.other	targeted cancer therapy
dc.subject.other	disulfiram
dc.subject.other	NPL4
dc.subject.other	replication stress
dc.subject.other	DNA damage
dc.subject.other	BRCA1
dc.subject.other	BRCA2
dc.subject.other	ATR pathway
dc.subject.other	PDAC
dc.subject.other	TCIRG1
dc.subject.other	ATP6V0a3
dc.subject.other	invasion
dc.subject.other	migration
dc.subject.other	matrix degradation
dc.subject.other	pH-regulation
dc.subject.other	autophagy
dc.subject.other	multidrug resistance in cancer
dc.subject.other	drug efflux pumps
dc.subject.other	ATP-binding cassette transporter
dc.subject.other	breast cancer resistance protein (BCRP)
dc.subject.other	ABCG2
dc.subject.other	pyrazolo-pyrimidine derivative
dc.subject.other	SCO-201
dc.subject.other	colorectal cancer
dc.subject.other	immunotherapy
dc.subject.other	inflammation
dc.subject.other	microsatellite instability
dc.subject.other	oncofetal chondroitin sulfate
dc.subject.other	chondroitin sulfate
dc.subject.other	cancer
dc.subject.other	solid tumors
dc.subject.other	target
dc.subject.other	pediatric cancer
dc.subject.other	VAR2
dc.subject.other	dexamethasone
dc.subject.other	thyroid cancer
dc.subject.other	microgravity
dc.subject.other	space environment
dc.subject.other	n/a
dc.title	Killing Cancer
dc.title.alternative	Discovery and Selection of New Target Molecules
dc.type	book
oapen.identifier.doi	10.3390/books978-3-03943-441-1
oapen.relation.isPublishedBy	46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn	9783039434404
oapen.relation.isbn	9783039434411
oapen.pages	302
oapen.place.publication	Basel, Switzerland

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