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Mitogen Activated Protein Kinases

Functions in Signal Transduction and Human Diseases

dc.contributor.editorTikkanen, Ritva
dc.contributor.editorNikolic-Paterson, David
dc.date.accessioned2021-05-01T15:16:32Z
dc.date.available2021-05-01T15:16:32Z
dc.date.issued2020
dc.identifierONIX_20210501_9783039280704_389
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/68643
dc.description.abstractMitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.otherRabdosia inflexa
dc.subject.otherinflammation
dc.subject.othergastric ulcer
dc.subject.othercytokines
dc.subject.otherMAPK
dc.subject.otherNF-κB
dc.subject.otherextracellular signal-regulated kinases 1/2
dc.subject.otherhyperoxia
dc.subject.otherbronchopulmonary dysplasia
dc.subject.otherHPAECs
dc.subject.otherangiogenesis
dc.subject.othercell cycle
dc.subject.otherSIRT1
dc.subject.otheroxidative stress
dc.subject.otherpsoriasis
dc.subject.otherantimicrobial peptide
dc.subject.othercecropin A
dc.subject.othertight junction protein
dc.subject.otherMEK/ERK signaling
dc.subject.otherporcine intestinal epithelial cell
dc.subject.otherextracellular signal-regulated kinase 5 (ERK5)
dc.subject.otherKv4.2
dc.subject.otherPC12 cells
dc.subject.otherinfantile myofibromatosis
dc.subject.otherreceptor tyrosine kinases
dc.subject.otherplatelet-derived growth factor receptor
dc.subject.otherprotein kinase inhibitors
dc.subject.othersunitinib
dc.subject.othererlotinib
dc.subject.otherFR180204
dc.subject.otherU0126
dc.subject.othertargeted therapy
dc.subject.otherapoptosis
dc.subject.otherERK1/2
dc.subject.otherJNKs
dc.subject.othermitochondrial dysfunction
dc.subject.otherneurodegeneration
dc.subject.otherneuro-inflammation
dc.subject.otherp38 MAPKs
dc.subject.otherParkinson’s disease
dc.subject.othermitogen-activated protein kinases (MAPKs)
dc.subject.otherMAPK kinetics
dc.subject.otherosteoclast differentiation
dc.subject.otherbone remodeling
dc.subject.otherDAPK
dc.subject.otherERK
dc.subject.otherp38
dc.subject.otherJNK
dc.subject.othermitogen-activated protein kinase pathway (MAPK pathway)
dc.subject.otherprotein tyrosine phosphatase interacting protein 51 (PTPIP51)
dc.subject.otherprotein-protein interaction (PPI)
dc.subject.othercancer signaling
dc.subject.otherSR
dc.subject.otherCR
dc.subject.otherCompatibility
dc.subject.otherT2DM
dc.subject.othermetabolic profiling
dc.subject.otherMAPK/PI3K/Akt signaling pathway
dc.subject.otherreactive oxygen species
dc.subject.otherPTPN6
dc.subject.otherSRC
dc.subject.otherDOK4
dc.subject.otherMKK4
dc.subject.otherMKK7
dc.subject.otherp53
dc.subject.otherDUSP1
dc.subject.otherSIRT2
dc.subject.otheratherosclerosis
dc.subject.otheraortic valve sclerosis
dc.subject.otheraortic valve stenosis
dc.subject.othernaphthalimide-metal complex conjugates
dc.subject.otherN-heterocyclic carbene
dc.subject.othermitochondria
dc.subject.otherROS
dc.subject.otherp38 MAPK
dc.subject.othercancer
dc.subject.otherFGF-induced signaling
dc.subject.otherFRS2
dc.subject.otherphosphorylation
dc.subject.otherdownregulation
dc.subject.othern/a
dc.titleMitogen Activated Protein Kinases
dc.title.alternativeFunctions in Signal Transduction and Human Diseases
dc.typebook
oapen.identifier.doi10.3390/books978-3-03928-071-1
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039280704
oapen.relation.isbn9783039280711
oapen.pages276
oapen.place.publicationBasel, Switzerland


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