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    Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

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    https://www.intechopen.com/books/umbilical-cord-blood-banking-for-clinical-application-and-regenerative-medicine
    Author(s)
    Ana Colette Mauricio
    Language
    English
    Show full item record
    Abstract
    Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future.
    URI
    https://directory.doabooks.org/handle/20.500.12854/61503
    Keywords
    Medicine; Stem Cell Research; Health Sciences; Cell Biology
    DOI
    10.5772/62607
    ISBN
    9789535128663, 9789535128656
    Publisher
    IntechOpen
    Publisher website
    https://www.intechopen.com/
    Publication date and place
    2017
    Pages
    258
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    • logo EUEuropean Union
      This project received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 871069.

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