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dc.contributor.authorDietrich, Alexander*
dc.date.accessioned2021-02-12T06:40:09Z
dc.date.available2021-02-12T06:40:09Z
dc.date.issued2019*
dc.date.submitted2019-06-26 08:44:07*
dc.identifier33718*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/61371
dc.description.abstractAlmost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include control of body temperature, transmitter release, mineral homeostasis, chemical sensing, and survival mechanisms in a challenging environment. The TRP channel superfamily covers six families: TRPC with C for “canonical”, TRPA with A for “ankyrin”, TRPM with M for “melastatin”, TRPML with ML for “mucolipidin”, TRPP with P for “polycystin”, and TRPV with V for “vanilloid”. Over the last few years, new findings on TRP channels have confirmed their exceptional function as cellular sensors and effectors. This Special Book features a collection of 8 reviews and 7 original articles published in “Cells” summarizing the current state-of-the-art on TRP channel research, with a main focus on TRP channel activation, their physiological and pathophysiological function, and their roles as pharmacological targets for future therapeutic options.*
dc.languageEnglish*
dc.subjectR5-920*
dc.subject.othern/a*
dc.subject.othertransient receptor potential channels*
dc.subject.otherphotochromic ligands*
dc.subject.otherelementary immunology*
dc.subject.otherPurkinje cell*
dc.subject.otherEPSC*
dc.subject.othersubstance P*
dc.subject.otherchemicals*
dc.subject.otherorgan toxicity*
dc.subject.otherlymphocytes*
dc.subject.otherHSP70*
dc.subject.otherphysiology*
dc.subject.otherbioavailable*
dc.subject.otherinflammatory bowel disease*
dc.subject.otherplatelets*
dc.subject.otherpollutants*
dc.subject.otheryeast*
dc.subject.otherregulatory T cells*
dc.subject.otherkinase*
dc.subject.otherSaccharomyces cerevisiae*
dc.subject.othermanganese*
dc.subject.othercerebellum*
dc.subject.otherTRP channel*
dc.subject.otherNHERF*
dc.subject.otherinflammation*
dc.subject.othernanoHPLC-ESI MS/MS*
dc.subject.otherTRPM7*
dc.subject.otherchemical probes*
dc.subject.otherTRPM8*
dc.subject.otherdorsal column nuclei*
dc.subject.otherTRPV2*
dc.subject.otherTRPV3*
dc.subject.othercalcitonin gene-related peptide*
dc.subject.otherTRPV1*
dc.subject.otherion channels*
dc.subject.othertransient receptor potential*
dc.subject.other2D gel electrophoresis*
dc.subject.otherMALDI-TOF MS(/MS)*
dc.subject.otherTRPV4*
dc.subject.otheroverproduction*
dc.subject.othersulfur mustard*
dc.subject.otheroxidative stress*
dc.subject.othergraft versus host disease*
dc.subject.othermenthol*
dc.subject.othertopical*
dc.subject.otherchemosensor*
dc.subject.otherAP18*
dc.subject.othercalcium signalling*
dc.subject.othermucosal epithelium*
dc.subject.othercuneate nucleus*
dc.subject.otherproduction platform*
dc.subject.otherTRPC channels*
dc.subject.otherulcerative colitis*
dc.subject.otherchannel structure*
dc.subject.otherxerostomia*
dc.subject.otherneutrophils*
dc.subject.othercardiovascular system*
dc.subject.otherTRPC5*
dc.subject.otherTRPC6*
dc.subject.otherTRPC3*
dc.subject.otherTRPC4*
dc.subject.othercalcium signaling*
dc.subject.otherprotein purification*
dc.subject.otheradipose tissue*
dc.subject.othertransient receptor potential (TRP) channels*
dc.subject.othersodium*
dc.subject.otherTH17*
dc.subject.otherdiacylglycerol*
dc.subject.otherhypersensitivity*
dc.subject.otherTRPY1*
dc.subject.otherGABAB*
dc.subject.otherHEK293*
dc.subject.otherthrombosis*
dc.subject.otherion channel*
dc.subject.otherTRPC*
dc.subject.otherpathophysiology*
dc.subject.otherSMAD*
dc.subject.othertoxicology*
dc.subject.otherendothelium*
dc.subject.othercalcium*
dc.subject.otherproteomics*
dc.subject.otherTRPA1*
dc.subject.othersalivary glands*
dc.subject.otherTRP channels*
dc.subject.otherlipid mediators*
dc.subject.othersensors*
dc.subject.otherradiation*
dc.subject.otherTRPM4 channel*
dc.subject.otherhuman medulla oblongata*
dc.subject.othermGluR1*
dc.subject.othersmall molecules*
dc.subject.otherTRPC3 pharmacology*
dc.titleTRP Channels in Health and Disease*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03921-083-1*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
oapen.relation.isbn9783039210824*
oapen.relation.isbn9783039210831*
oapen.pages266*
oapen.edition1st*


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