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    Oncogenes and Carcinogenesis

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    https://www.intechopen.com/books/oncogenes-and-carcinogenesis
    Author(s)
    Pinar Erkekoglu
    Language
    English
    Show full item record
    Abstract
    Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
    URI
    https://directory.doabooks.org/handle/20.500.12854/55222
    Keywords
    Life Sciences; Genetics and Molecular Biology; Oncology; Biochemistry; Cancer Biology
    DOI
    10.5772/intechopen.74727
    ISBN
    9781789851724, 9781789851717
    Publisher
    IntechOpen
    Publisher website
    https://www.intechopen.com/
    Publication date and place
    2019
    Pages
    106
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    Credits


    • logo ScossScoss
    • logo Investir l'avenirInvestir l'avenir
    • logo MESRIMESRI
    • logo EUEuropean Union
      This project received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 871069.

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