Export citation

Show simple item record

dc.contributor.authorVolker Schirrmacher*
dc.contributor.authorPhilippe Fournier*
dc.date.accessioned2021-02-11T15:08:10Z
dc.date.available2021-02-11T15:08:10Z
dc.date.issued2015*
dc.date.submitted2016-02-05 17:24:33*
dc.identifier18596*
dc.identifier.issn16648714*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/49124
dc.description.abstractOncolytic viruses (OVs) have emerged as a promising anticancer treatment. OVs selectively infect, replicate in, and kill tumor cells. Oncolytic viral therapy occurs in two phases: an initial phase where the virus mediates direct oncolysis of tumor cells, and a second phase where an induced post-oncolytic immune response continues to mediate tumor destruction and retards progression of the disease. For a long time, the therapeutic efficacy was thought to depend mainly on the direct viral oncolysis based on their tumor selective replication and killing activities. But the post-oncolytic anti-tumor activity induced by the OV therapy is also a key factor for an efficient therapeutic activity. The topic adresses various strategies how to optimize OVs anti-tumor activity.*
dc.languageEnglish*
dc.relation.ispartofseriesFrontiers Research Topics*
dc.subjectR5-920*
dc.subjectRC581-607*
dc.subjectRC254-282*
dc.subject.otheranti-tumor activity*
dc.subject.otherimmunovirotherapy*
dc.subject.otheroncolytic virus*
dc.subject.otheroncolytic virotherapy*
dc.subject.othertumor-associated antigen*
dc.subject.otherimmunotherapeutic approaches*
dc.subject.otheranti-viral response*
dc.titleHarnessing oncolytic virus-mediated immunity*
dc.typebook
oapen.identifier.doi10.3389/978-2-88919-450-6*
oapen.relation.isPublishedBybf5ce210-e72e-4860-ba9b-c305640ff3ae*
virtual.oapen_relation_isPublishedBy.publisher_nameFrontiers Media SA
virtual.oapen_relation_isPublishedBy.publisher_websitewww.frontiersin.org
oapen.relation.isbn9782889194506*
oapen.pages110*


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/