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dc.contributor.authorLee, Nikki*
dc.contributor.authorYee, Nelson*
dc.date.accessioned2021-02-11T09:28:03Z
dc.date.available2021-02-11T09:28:03Z
dc.date.issued2019*
dc.date.submitted2019-12-09 11:49:15*
dc.identifier42510*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/42637
dc.description.abstractIdentification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases.*
dc.languageEnglish*
dc.subjectR5-920*
dc.subject.othern/a*
dc.subject.otherliver graft injury*
dc.subject.otherHFE*
dc.subject.otherneurokinin*
dc.subject.otherchemotherapy*
dc.subject.otherintestinal tumors*
dc.subject.othertherapeutic targets*
dc.subject.otherbiliary tract carcinoma*
dc.subject.otherhepatocellular carcinoma*
dc.subject.otherclinical trial*
dc.subject.othercell adhesion molecules*
dc.subject.othercolorectal cancer*
dc.subject.otherbiomarkers*
dc.subject.otherphenotypic mosaics*
dc.subject.othergastrointestinal oncology*
dc.subject.otherAsian Cancer Research Group (ACRG)*
dc.subject.otherbiomarker*
dc.subject.otherpsychosocial support*
dc.subject.otherprecision therapy*
dc.subject.otherpancreatic carcinoma*
dc.subject.otherprecision medicine*
dc.subject.otherLiver transplantation*
dc.subject.otherpredictive biomarkers*
dc.subject.otherCD274*
dc.subject.othercholecystokinin*
dc.subject.otherThe Cancer Genome Atlas (TCGA)*
dc.subject.othergastrin*
dc.subject.otherpembrolizumab*
dc.subject.otherimmunotherapy*
dc.subject.othergastrin-releasing peptide*
dc.subject.otherstereotactic body radiation therapy*
dc.subject.otherimmunohistochemistry*
dc.subject.othergastric carcinoma*
dc.subject.otherliver transplant*
dc.subject.otherCAM invasion assay*
dc.subject.otherintragraft gene expression profiles*
dc.subject.othermolecular profiling*
dc.subject.othertargeted therapy*
dc.subject.otherneurotensin*
dc.subject.otherintestinal disorder*
dc.subject.otherramucirumab*
dc.subject.othernext-generation sequencing*
dc.subject.othercolorectal carcinoma*
dc.subject.othertumor progenitor*
dc.subject.othercirculating tumor cells*
dc.subject.othergastrointestinal malignancies*
dc.subject.otherbombesin*
dc.subject.othertrastuzumab*
dc.subject.othersomatostatin*
dc.subject.otherzebrafish*
dc.subject.otherG protein–coupled receptors*
dc.titleCancer Biomarkers and Targets in Digestive Organs*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03921-464-8*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
virtual.oapen_relation_isPublishedBy.publisher_nameMDPI - Multidisciplinary Digital Publishing Institute
virtual.oapen_relation_isPublishedBy.publisher_websitewww.mdpi.com/books
oapen.relation.isbn9783039214648*
oapen.relation.isbn9783039214631*
oapen.pages146*
oapen.edition1st*


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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/