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Genetics and Epigenetics in Complex Diseases

dc.contributor.editorLopez-Lopez, Elixabet
dc.date.accessioned2023-07-14T14:22:56Z
dc.date.available2023-07-14T14:22:56Z
dc.date.issued2023
dc.identifierONIX_20230714_9783036578576_4
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/101305
dc.description.abstractMany of the most common diseases are influenced by a combination of multiple factors, which include environmental effectors as well as genetic and epigenetic variations. Therefore, these diseases are grouped under the term “complex” diseases because, from the point of view of genetics, they cannot be explained by simple Mendelian inheritance. The aim of this special issue was to identify genetic and epigenetic factors involved in such diseases in order to improve not only the knowledge of risk factors for those diseases, which could be of help for prevention, but also the understanding and characterization of each disease and to optimize and personalize the treatment.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)en_US
dc.subject.otherchromatin remodeling
dc.subject.othercircular RNA
dc.subject.otherDNA methylation
dc.subject.otherhistone modification
dc.subject.othernon-coding RNA
dc.subject.otheroncogenes
dc.subject.othertumor suppressor genes
dc.subject.othertumor virus
dc.subject.otherchronic lymphocytic leukemia
dc.subject.otherCLL
dc.subject.otherSF3B1 mutation
dc.subject.otherNOTCH
dc.subject.otherIKAROS
dc.subject.othersyncope
dc.subject.othervasovagal syncope
dc.subject.othergenetics
dc.subject.othercomplex disorders
dc.subject.othersusceptibility
dc.subject.othertwin studies
dc.subject.otherfamily studies
dc.subject.othercandidate gene association studies
dc.subject.othergenome-wide studies
dc.subject.otheracute myeloid leukemia
dc.subject.otherpediatric
dc.subject.othertrio sequencing
dc.subject.othergermline cancer predisposition
dc.subject.otherPOT1
dc.subject.othershelterin complex
dc.subject.otherpsoriasis
dc.subject.otherpsoriatic arthritis
dc.subject.otherNF-κB
dc.subject.othercomorbidities
dc.subject.othergenetic architecture
dc.subject.otherSKP1
dc.subject.otherCUL1
dc.subject.otherRBX1
dc.subject.otherSKP2
dc.subject.otherFBXW7
dc.subject.otherFBXO5
dc.subject.otherSCF complex
dc.subject.othergenome instability
dc.subject.otherchromosome instability
dc.subject.othercancer
dc.subject.otherVDBP
dc.subject.othervitamin D binding protein
dc.subject.otherrs7041
dc.subject.otherrs4588
dc.subject.otherbone density
dc.subject.otherdiabetes
dc.subject.otherobesity
dc.subject.otherCOPD
dc.subject.otherpulmonary tuberculosis
dc.subject.otherSNP
dc.subject.otherMD
dc.subject.otherPD
dc.subject.otherCD33
dc.subject.otherAlzheimer’s disease
dc.subject.othersialic acid
dc.subject.otherphagocytosis
dc.subject.otherKLF14
dc.subject.otherbody shape indices
dc.subject.othermetabolic traits
dc.subject.otherdifferential effect
dc.subject.othergenetic variants
dc.subject.otherresistin
dc.subject.othersoluble suppression of tumorigenicity 2
dc.subject.otherweighted genetic risk score
dc.subject.otherTaiwan Biobank
dc.subject.othercoronary artery disease
dc.subject.otherall-cause mortality
dc.subject.othermajor adverse cardiac events
dc.subject.otheracute lymphoblastic leukemia
dc.subject.otherRAD21
dc.subject.othercohesin complex
dc.subject.othern/a
dc.titleGenetics and Epigenetics in Complex Diseases
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-7856-9
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036578576
oapen.relation.isbn9783036578569
oapen.pages238
oapen.place.publicationBasel


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