Advances in Molecular Genetics of Brain Tumors

doi:10.3390/books978-3-0365-6645-0

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https://mdpi.com/books/pdfview/book/6878

Contributor(s)

Pećina-Šlaus, Nives (editor)

Jovčevska, Ivana (editor)

Language

English

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Abstract

This reprint encompasses a number of articles that focus on the molecular blueprint of brain tumors. A collection of relevant papers in the rapidly expanding field of brain tumor molecular genetics broadens our knowledge about the biology of brain tumors, and inspires further studies that will improve the diagnosis and clinical management of brain tumors. Due to the great heterogeneity of brain tumors it is important to research and understand every aspect of their initiation, progression and metastasis in order to design better diagnostic and therapeutic approaches for their clinical management and patient benefit.

URI

https://directory.doabooks.org/handle/20.500.12854/98825

Keywords

DVL1; PDZ domain; β-catenin; Wnt signaling pathway; intracranial meningioma; microglia; glioblastoma; olfactomedin-like 3; TGFβ; Glioblastoma; Doublecortin; DCX; OLIG2; NES; single cell RNA-seq; immunohistochemistry; immunofluorescence; brain tumours; brain tumor; GBM; cancer stem cell; BIRC3; BMP4; stemness; pediatric glioblastoma; temozolomide; NKCC1; KCC2; EZH2; PCNA; CAM; cancer; neurodegeneration; glioma; Drosophila; disease model; PI3K; EGFR; genetics; schwannoma; NF2; bevacizumab; VEGF; SH3PXD2A-HTRA1 fusion; molecular targeted therapy; IDH1 mutation; redox household; nicotinamide phosphoribosyltransferase; NAD+ synthesis; cancer metabolism; pentose phosphate pathway; cell proliferation; miRNA; hypoxia; angiogenesis; treatment-related changes; true progression; pseudoprogression; radiation necrosis; biomarkers; 18F-FET PET; IDH mutation; functional precision oncology; drug sensitivity; prognostic biomarkers; systematic review; meta-analysis; cancer pathway; mRNA; multicriterial analysis; n/a