New Insights into the Pathogenesis and Therapies of IgA Nephropathy
Suzuki, Hitoshi (editor)
Novak, Jan (editor)
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a frequent cause of kidney failure. Better understanding of the pathogenesis of IgAN and the related genetic, immunological, and cellular susceptibility factors are needed to enable the development of effective disease-specific therapy. This book brings together international experts to provide clinical and experimental studies and reviews with an emphasis on early diagnosis, prognosis, disease pathogenesis, determination of disease activity, and new strategies for treatment for IgAN.
Keywordsobesity; mesangial matrix expansion; body mass index; IgA nephropathy; IgA Vasculitis; IgA Nephropathy; adults; children; presentation; physiopathology; genetics; prognosis; treatment; IgA; clinical trials; kidney mesangium; mouse model; aberrantly glycosylated IgA1; galactose-deficient IgA1; glycosylation of IgA1; biomarker; complement C3; O-glycosylation; IgA1; autoantibody; immune complex; complement; kidney; nephrology; IgA vasculitis; nephritis; kidney biopsy; plasma cells; CD38; renal pathology; urinary galactose-deficient IgA1; KM55; crescents; proteinuria; glomerular filtration rate; Oxford score; n/a
Publication date and placeBasel, 2022