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dc.contributor.editorChalikian, Tigran
dc.contributor.editorVölker, Jens
dc.date.accessioned2023-02-02T16:26:46Z
dc.date.available2023-02-02T16:26:46Z
dc.date.issued2023
dc.identifierONIX_20230202_9783036560984_29
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/96628
dc.description.abstractThis Special Issue comprises 15 papers broadly outlining current trends in nucleic acid biophysics. It contains original research papers and reviews on structure, stability, and interactions of canonical and non-canonical nucleic acids. The authors describe the use of established, time-honored experimental and computational techniques as well as their more recently developed counterparts. Molecular insights that can be gained from the papers collected in this issue range from the fundamental to the applied with emphasis on biological functions and biomedical prospects of nucleic acids. The collection is not meant to be exhaustive, but to highlight recent advances from select laboratories worldwide. Nevertheless, it represents a useful guide for scientists who wish to familiarize themselves with biophysical topics in nucleic acid research. This Special Issue will be useful both for researchers who study fundamental aspects of nucleic acid structure, stability, and dynamics, as well as for those that are mainly interested in practical biological and biomedical applications of nucleic acids.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.othernucleic acid structures
dc.subject.othernucleic acid conformation
dc.subject.otherbiological structure database
dc.subject.otherDNA
dc.subject.otherRNA
dc.subject.othervalidation standards
dc.subject.otherG-quadruplex
dc.subject.otherreplication
dc.subject.otherthermodynamics
dc.subject.otherligand
dc.subject.othertopology
dc.subject.otherquadruplex-duplex hybrids
dc.subject.otherminor groove binding drugs
dc.subject.otherstability
dc.subject.otheroptical spectroscopy
dc.subject.othernucleic acids
dc.subject.othercharge
dc.subject.otherelectrostatic potential
dc.subject.otherab initio methods
dc.subject.otherNMR spectroscopy
dc.subject.othermolecular dynamics
dc.subject.otherforcefield
dc.subject.otherAMBER
dc.subject.otherB-DNA
dc.subject.otherDNA-hairpin
dc.subject.otherperchlorates
dc.subject.otherbrines
dc.subject.otherpressure
dc.subject.otherMars
dc.subject.otherhabitability
dc.subject.otherDNA minor groove binder
dc.subject.othermixed base-pair DNA sequences
dc.subject.othersequence selectivity
dc.subject.otherligand–DNA complex thermodynamic
dc.subject.othermolecular curvature
dc.subject.otherheterocyclic diamidine
dc.subject.otherbiosensor
dc.subject.othercalorimetry
dc.subject.otherDNA conjugate
dc.subject.othermetal ion
dc.subject.othertriple helix
dc.subject.othersilver ion
dc.subject.otherlanthanide
dc.subject.otherATP sensor
dc.subject.otheraptamer
dc.subject.otherterpyridine
dc.subject.othersequence edition
dc.subject.otherDNAzyme
dc.subject.othermolecular dynamics simulation (MD)
dc.subject.otherpotential of mean force (PMF)
dc.subject.otherdsDNA–dsDNA interactions
dc.subject.otherflexibility
dc.subject.otherorigins of life
dc.subject.otherDNA-protein networks
dc.subject.otherprotocells
dc.subject.otherDNA sequence-dependent structure
dc.subject.otherDNA deformability
dc.subject.otherDNA sequence context
dc.subject.otherDNA curvature
dc.subject.otherDNA minicircles
dc.subject.otherhydrostatic pressure
dc.subject.othervolume
dc.subject.otherCD spectroscopy
dc.subject.otherG-quadruplexes
dc.subject.otherpotassium
dc.subject.otherpolymorphism
dc.subject.otherkinetics
dc.subject.otherfolding
dc.subject.otherkinetic models
dc.subject.otherfitting
dc.subject.otheraurintricarboxylic acid (ATA)
dc.subject.othersalicylic acid polymers
dc.subject.othermethylene-salicylic acid
dc.subject.otherSARS-CoV-2
dc.subject.otherRNA-dependent RNA polymerase (RdRp)
dc.subject.otheryeast ribosomes
dc.subject.otherhuman serum albumin (HSA)
dc.subject.othermolecular recognition
dc.subject.otherbiological function and viral disease
dc.subject.otherinhibitor binding
dc.subject.othersingle-molecule biophysics
dc.subject.othernucleic acid thermodynamics
dc.subject.otherstatistical mechanics
dc.subject.otherfluctuation theorems
dc.subject.othercomputational biophysics
dc.subject.othern/a
dc.subject.otherdrug discovery
dc.subject.otherdrug-target interactions
dc.subject.otherthermodynamic binding signatures
dc.subject.otherisothermal titration calorimetry
dc.subject.otherlead optimization
dc.subject.otherfragment-based drug discovery
dc.subject.otherdrug-like properties
dc.subject.otherenthalpic efficiency
dc.subject.othergroup efficiency
dc.subject.otherlipophilic efficiency
dc.titleBiophysics of Nucleic Acids Celebrating the 75th Birthday of Professor Kenneth J. Breslauer
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-6097-7
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036560984
oapen.relation.isbn9783036560977
oapen.pages282
oapen.place.publicationBasel


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