Show simple item record

dc.contributor.authorCOPPI, Elisabetta
dc.date.accessioned2022-06-02T04:17:23Z
dc.date.available2022-06-02T04:17:23Z
dc.date.issued2008
dc.date.submitted2022-05-31T10:14:26Z
dc.identifierONIX_20220531_9788884539052_113
dc.identifier2612-8020
dc.identifierhttps://library.oapen.org/handle/20.500.12657/54829
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/82784
dc.description.abstractPurinergic nucleotides and nucleosides (ATP, ADP, AMP and adenosine) are essential intracellular metabolites involved in a number of cellular processes, from energy supply to protein phosphorylation. However, in the last years, several studies demonstrated their involvement in cell signalling by the activation of specific membrane receptors (P1 and P2) and their role as neurotransmitters began to be investigated. The present work was aimed to clarify the effects of purinergic neurotransmission in different cell systems by using electrophysiological techniques. Relevant results of this research include the observation that P1 and P2 receptors play a deleterious role during "in vitro" ischemia in the rat brain, and the first demonstration of P2 receptor expression and function in a line of adult human mesenchymal stem cells.
dc.languageEnglish
dc.relation.ispartofseriesPremio Tesi di Dottorato
dc.rightsopen access
dc.subject.classificationbic Book Industry Communication::M Medicine
dc.subject.otherChimica
dc.subject.otherChimica inorganica
dc.subject.otherFisiologia
dc.subject.otherMetabolismo
dc.subject.otherAcidi nucleici
dc.subject.otherOpen Access
dc.titlePurines as Transmitter Molecules: Electrophysiological Studies on Purinergic Signalling in Different Cell Systems
dc.typebook
oapen.identifier.doi10.36253/978-88-8453-905-2
oapen.relation.isPublishedBy2ec4474d-93b1-4cfa-b313-9c6019b51b1a
oapen.relation.isbn9788884539052
oapen.relation.isbn9788884539045
oapen.relation.isbn9788892737891
oapen.pages192
oapen.place.publicationFirenze
dc.seriesnumber1


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

open access
Except where otherwise noted, this item's license is described as open access