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dc.contributor.authorPolito, Cristina
dc.date.accessioned2022-06-02T04:01:27Z
dc.date.available2022-06-02T04:01:27Z
dc.date.issued2011
dc.date.submitted2022-05-31T10:18:02Z
dc.identifierONIX_20220531_9788866550419_247
dc.identifier2612-8020
dc.identifierhttps://library.oapen.org/handle/20.500.12657/54963
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/81980
dc.description.abstractThe present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus.
dc.languageEnglish
dc.relation.ispartofseriesPremio Tesi di Dottorato
dc.rightsopen access
dc.subject.classificationthema EDItEUR::M Medicine and Nursingen_US
dc.titleMolecular imaging in Parkinson's disease
dc.typebook
oapen.identifier.doi10.36253/978-88-6655-041-9
oapen.relation.isPublishedBy2ec4474d-93b1-4cfa-b313-9c6019b51b1a
oapen.relation.isbn9788866550419
oapen.relation.isbn9788866550372
oapen.relation.isbn9788892736450
oapen.pages68
oapen.place.publicationFirenze
dc.seriesnumber18


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