Osteoarthritis: From Molecular Pathways to Therapeutic Advances
Veronese, Nicola (editor)
In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.
Keywordsosteoarthritis; cartilage; type II collagen; matrix metalloproteinases; MMP-13; regulation; inhibitor; NO synthase; Interleukin-1β; chondrocytes; mitochondrial dysfunction; mesenchimal stem cells; chondrocytic commitment; autophagy; miRNAs; hydrostatic pressure; adipokines; visfatin; Wnt/β-catenin; mechanical loading; obesity; microRNA; oxidative stress; vibrational spectroscopy; near-infrared spectroscopy; infrared spectroscopy; Raman spectroscopy; early diagnosis; exercise; physical activity; nutraceuticals; dietary supplements; inflammation; aging; inflammaging; osteochondral explant culture; joint modelling; pharmacological assay; native tissue analysis; hexosamine biosynthetic pathway; cartilage trauma; post-traumatic osteoarthritis; O-GlcNAcylation; glucosamine; cell death; therapy; sex as a biological variable; whole transcriptome sequencing; molecules; TGF-β; SMAD2/3 signaling; linker modifications; meniscus; proteomics; MRM; ECM; celecoxib; glucosamine sulfate; chondroprotection; NF-κB; cytokines; chemokines; pathogenesis; biomarker; chondrocyte; IL-1β; IFNγ, IL-17; IL-4; RNA-Seq; hypertrophy; remodeling; angiogenesis; chondroitin; collagen; methylsulfonylmethane; vitamin C; vitamin D; hyaluronic acid
Webshop linkhttps://mdpi.com/books/pdfview ...
Publication date and placeBasel, 2022
Research & information: general
Biology, life sciences