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dc.contributor.editorRonellenfitsch, Ulrich
dc.date.accessioned2022-01-11T13:42:33Z
dc.date.available2022-01-11T13:42:33Z
dc.date.issued2021
dc.identifierONIX_20220111_9783036509204_533
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/76798
dc.description.abstractRecent decades have seen remarkable advances in the treatment of upper gastrointestinal malignancies, i.e., adenocarcinoma and squamous cell carcinoma as well as gastrointestinal stromal and other rare tumors of the esophagus and stomach. While, historically, surgical resection has been the sole treatment for these tumors, multimodal therapies have meanwhile proven their efficacy. At present, pre- and postoperative chemotherapy and radiotherapy, targeted drug therapy, and stage-specific surgical approaches are all indispensable cornerstones of an individualized treatment for upper gastrointestinal malignancies. With such multimodal treatment, better outcomes comprising improved quality of life and prolonged survival have been achieved for patients. However, for many tumor entities and stages, the ideal combination and sequence of treatments is still being evaluated in clinical trials. Moreover, the value of novel approaches such as immunotherapy or robotic surgery remains a matter of research. In this Special Issue of Cancers, up-to-date original research, short communications, and comprehensive review articles on all modalities playing a role in the treatment of upper gastrointestinal malignancies have been published.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine
dc.subject.othergastric cancer
dc.subject.othergastrectomy
dc.subject.othercomplications
dc.subject.otheroutcome
dc.subject.othersurvival
dc.subject.otherlymph node ratio
dc.subject.otherneoadjuvant chemotherapy
dc.subject.otherconversion surgery
dc.subject.othercancer dormancy
dc.subject.othernuclear receptor NR2F1
dc.subject.otherclinical pathways
dc.subject.othergastric surgery
dc.subject.otheroncological gastrectomy
dc.subject.otherquality of care
dc.subject.otheroutcomes
dc.subject.otherstandardization
dc.subject.otheradjuvant therapy
dc.subject.othergastrointestinal tract
dc.subject.othergenetic diagnosis
dc.subject.otherradiosensitivity
dc.subject.othermortality
dc.subject.otherfailure to rescue
dc.subject.otherimmunotherapy
dc.subject.othergenetics
dc.subject.otheresophageal cancer
dc.subject.othermultidisciplinary
dc.subject.othergastric/gastroesophageal cancer
dc.subject.otherperioperative chemotherapy
dc.subject.otheroverall survival
dc.subject.otherrelapse-free survival
dc.subject.otherskeletal muscle index
dc.subject.otheresophagectomy
dc.subject.othernutritional status
dc.subject.othersarcopenia
dc.subject.otheresophageal anastomosis
dc.subject.otherminimally invasive surgery
dc.subject.otherinduction chemotherapy
dc.subject.otherchemo-radiotherapy
dc.subject.otherneoadjuvant treatment
dc.subject.otheresophageal squamous cell carcinoma
dc.subject.othermultimodal treatment
dc.subject.otherneoadjuvant chemoradiotherapy
dc.subject.otherdefinitive chemoradiotherapy
dc.subject.otherLauren histotype
dc.subject.othergastrointestinal stromal tumor
dc.subject.otherneuroendocrine tumor
dc.subject.otherMALT lymphoma
dc.subject.othermucosal resection
dc.subject.othersubmucosal dissection
dc.subject.otherGIST
dc.subject.otherstomach
dc.subject.otherneoadjuvant therapy
dc.subject.otherimatinib
dc.subject.otherorgan preservation
dc.subject.othersquamous cell esophageal cancer
dc.subject.othergastro-esophageal reflux disease
dc.subject.otherBarrett’s esophagus
dc.subject.otherearly adenocarcinoma of esophagus
dc.subject.otherendoscopic submucosal dissection
dc.subject.otherendoscopic mucosal resection
dc.subject.othern/a
dc.titleMultimodal Therapy of Upper Gastrointestinal Malignancies
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-0921-1
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036509204
oapen.relation.isbn9783036509211
oapen.pages272
oapen.place.publicationBasel, Switzerland


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