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dc.contributor.editorManzo, Emiliano
dc.date.accessioned2022-01-11T13:38:35Z
dc.date.available2022-01-11T13:38:35Z
dc.date.issued2021
dc.identifierONIX_20220111_9783036517681_406
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/76671
dc.description.abstractMarine natural products are characterized by high chemical diversity, biochemical specificity, and other molecular properties that make them favorable as lead structures for drug discovery. In this field, one of the main problems is often the reduced natural availability of isolated substances, which can complicate both the structural characterization and possible future developments. For these reasons, the study of bioactive marine metabolites should rely on the development of chemical synthesis and synthetic strategies aimed at the preparation of pure compounds and analogs both for structural confirmation and/or for the large-scale preparation necessary for future applications. Moreover, natural products can be a crucial starting point for the preparation of molecules structurally inspired by the latter, opening the path to new classes of biologically active compounds with pharmacological potential. This book collects original research articles regarding synthetic strategies for secondary marine metabolites and/or analogs that favor applications of these molecules and/or solve structural challenges common in the field of natural substances.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::C Language and Linguisticsen_US
dc.subject.otherorganic synthesis
dc.subject.othermeroterpenoids
dc.subject.otherthiazinoquinones
dc.subject.otherantiproliferative activity
dc.subject.otherG0/G1 cell-cycle arrest
dc.subject.othercytostatic
dc.subject.othersolid tumor cell lines
dc.subject.otheralkylglycerol (AKG)
dc.subject.otherricinoleic acid (RA)
dc.subject.otherantimicrobial activity
dc.subject.otherstructure–activity relationship (SAR) studies
dc.subject.otherantibiotics (gentamicin
dc.subject.othertetracycline
dc.subject.otherciprofloxacin and ampicillin)
dc.subject.othermarine-inspired
dc.subject.otherbreast cancer
dc.subject.otherbis-indoles
dc.subject.othersynthesis
dc.subject.otherapoptosis
dc.subject.othercarbohydrates
dc.subject.otherpolysaccharides
dc.subject.othersemi-synthesis
dc.subject.othersulfation
dc.subject.otherglycosylation
dc.subject.otherfucose
dc.subject.otherfucosylated chondroitin sulfate
dc.subject.othermarine natural product
dc.subject.otherlargazole
dc.subject.otherHDAC inhibitors
dc.subject.othermodification
dc.subject.otherfluoro olefin
dc.subject.othertotal synthesis
dc.subject.othernatural product
dc.subject.other7-deazapurine nucleoside
dc.subject.otherdisaccharide nucleoside
dc.subject.othertubercidin
dc.subject.otheraureol
dc.subject.othertetracyclic meroterpenoids
dc.subject.othernatural products synthesis
dc.subject.otherlabdane scaffold
dc.subject.otherbioactive diterpenes
dc.subject.othersclareolide
dc.subject.otherstructure-activity relationships
dc.subject.otherTRPV4 channel
dc.subject.otheramides/esters
dc.subject.otherCOVID-19
dc.subject.otherSARS-CoV-2
dc.subject.otherlipophilic iminosugars
dc.subject.otherpolymer-supported triphenyl phosphine
dc.subject.othercholesterol
dc.subject.otherantibacterial iminosugars
dc.subject.othern/a
dc.titleSynthesis of Marine Natural Products and Molecules Inspired by Marine Substances
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-1767-4
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036517681
oapen.relation.isbn9783036517674
oapen.pages147
oapen.place.publicationBasel, Switzerland


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