Biopolymers in Drug Delivery and Regenerative Medicine
García-González, Carlos A. (editor)
Gaudio, Pasquale Del (editor)
Starbird, Ricardo (editor)
Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology. The main aim of the Special Issue on “Biopolymers in Drug Delivery and Regenerative Medicine” is to gather recent findings and current advances on biopolymer research for biomedical applications, particularly in regenerative medicine, wound healing, and drug delivery. Contributions to this issue can be as original research or review articles and may cover all aspects of biopolymer research, ranging from the chemical synthesis and characterization of modified biopolymers, their processing in different morphologies and hierarchical structures, as well as their assessment for biomedical uses.
Keywordscurcumin; pectin aerogels; chitosan coating; burst release; controlled release; Keratose; drug-coated balloon; paclitaxel; drug delivery; pre-clinical; peripheral arterial disease; endovascular; cellulose phosphate; cellulose phosphate aerogel; interconnected porosity; supercritical carbon dioxide; tetrabutylammonium fluoride; TBAF/DMSO; polysaccharide; κ-carrageenan; dexamethasone; electrochemical active deliver system; doping agent; charged molecule; conductive polymers; colorectal cancer; antioxidants; 5-fluorouracil; polymer nanomaterials; nanocapsules; chemotherapy; cryogel; starch; NMR spectroscopy; morphology; drug release; polysaccharides; hydrogels; prilling; droplets; ionotropic gelation; drying; xerogels; cryogels; aerogels; lipid microparticles; PGSS®; supercritical CO2; modeling; solvent-free technology; biomaterials; porous materials; biomimetic; multi-stimulation; tissue engineering; n/a
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Publication date and placeBasel, Switzerland, 2021