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dc.contributor.editorPuca, Annibale
dc.contributor.editorCaruso, Calogero
dc.date.accessioned2022-01-11T13:31:37Z
dc.date.available2022-01-11T13:31:37Z
dc.date.issued2021
dc.identifierONIX_20220111_9783036509808_163
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/76427
dc.description.abstractPeople around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: generalen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.otheraging
dc.subject.otheralternative therapy
dc.subject.othercomposition of royal jelly
dc.subject.otherdietary interventions
dc.subject.otherhealthspan
dc.subject.otherlifespan
dc.subject.otherlongevity
dc.subject.otherroyal jelly
dc.subject.otherIGF-1
dc.subject.otheroxidative stress
dc.subject.otherageing
dc.subject.othernematode
dc.subject.otherimmunosenescence
dc.subject.otherprobiotic bacteria
dc.subject.otherpathogen protection
dc.subject.otherfood allergy
dc.subject.otherelderly
dc.subject.otherhypersensitivity
dc.subject.othergut
dc.subject.otherallergy
dc.subject.otherinflammation
dc.subject.otherredoxomics
dc.subject.otherglutathione
dc.subject.othermeniere’s disease
dc.subject.otherneurodegenerative diseases
dc.subject.otherhealthy aging
dc.subject.otherDNA methylation
dc.subject.otherepigenetic clocks
dc.subject.othertelomere length
dc.subject.othercentenarians
dc.subject.otherexosomes
dc.subject.otherserum
dc.subject.otherfunctional enrichment analysis
dc.subject.otheringenuity pathway analysis
dc.subject.othermiRNA-mRNA networks
dc.subject.otheraging-related disease
dc.subject.otherDi (2-Ethylhexyl) pthalate
dc.subject.otherHericium erinaceus
dc.subject.othervitagenes
dc.subject.otherapoptosis
dc.subject.othermitochondrial respiratory complexes
dc.subject.otherC. elegans
dc.subject.otherpolyphenols
dc.subject.otherolive oil
dc.subject.otherParkinson’s disease
dc.subject.otherβ-Dystroglycan
dc.subject.othercellular senescence
dc.subject.otherlamin B1
dc.subject.otherDNA-damage response
dc.subject.otherdefective mitosis
dc.subject.othern/a
dc.titleCentenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-0981-5
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036509808
oapen.relation.isbn9783036509815
oapen.pages204
oapen.place.publicationBasel, Switzerland


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