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dc.contributor.editorHildebrand, Frank
dc.contributor.editorHorst, Klemens
dc.date.accessioned2021-05-01T15:49:15Z
dc.date.available2021-05-01T15:49:15Z
dc.date.issued2020
dc.identifierONIX_20210501_9783039437771_1167
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/69421
dc.description.abstractTrauma represents a leading cause of death, particularly in the younger population. Traumatic brain injury and hemorrhage are the most common causes of early death, whereas complications such as infections, (multi-)organ failure and “persistent inflammation, immunosuppression, and catabolism syndrome” (PICS) represent relevant factors for late adverse outcomes. Pre- and intra-hospital diagnostic and therapeutic standard operating procedures have been shown to beneficially influence posttraumatic outcome. However, development of patient-specific diagnostic and therapeutic strategies remains challenging due to uncertainties regarding the assessment of the individual risk profile. Furthermore, the relevance of prevention and rehabilitation measures to avoid unfavorable long-term consequences of trauma is not fully elucidated. With this Special Issue, we wanted to reflect the current knowledge about the pathomechanisms associated with the impact of severe injury and its consequences for the further clinical course on the one hand, and to point out new insights in regard to diagnostic and therapeutic approaches on the other hand. Furthermore, interesting aspects for future directions for the care of severely injured patients are illustrated.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::M Medicine and Nursingen_US
dc.subject.otherPICS
dc.subject.othertrauma
dc.subject.otherimmunology
dc.subject.otherinfectious complications
dc.subject.othervirtual reality
dc.subject.otherburn
dc.subject.otherhand
dc.subject.othermTICCS
dc.subject.otherTICCS
dc.subject.othermassive transfusion
dc.subject.othershock
dc.subject.othermultiple trauma
dc.subject.otherpolytrauma
dc.subject.otherbleeding
dc.subject.othertransfusion
dc.subject.otherArthroscopy-assisted corrective osteotomy
dc.subject.othertibial plateau malunion
dc.subject.othertibial plateau nonunion
dc.subject.otherproliferation
dc.subject.otherlymphocytes
dc.subject.otherregulatory T cells
dc.subject.otherIL-10
dc.subject.othersepsis
dc.subject.othercomplement
dc.subject.otherpatients
dc.subject.otherextracorporeal shock wave therapy
dc.subject.otherhypertrophic scar
dc.subject.otherhand function
dc.subject.otherrisk factors
dc.subject.otherknee joint injuries
dc.subject.otherknee dislocation
dc.subject.otherligament injuries
dc.subject.othertraumatic brain injury (TBI)
dc.subject.otherrisk prediction
dc.subject.otherbiomarker
dc.subject.otherIL-6
dc.subject.otherposttraumatic inflammation
dc.subject.otherS100b
dc.subject.otherNSE
dc.subject.otherGFAP
dc.subject.othermultiple-injured patient
dc.subject.otherspine injury
dc.subject.otherAOSpine classification
dc.subject.othertime to surgery
dc.subject.otherspinal cord injury
dc.subject.otherrehabilitation
dc.subject.otherexercises
dc.subject.otherhemostasis
dc.subject.othervenous thrombosis
dc.subject.othersarcopenia
dc.subject.otherprevalence
dc.subject.othermortality
dc.subject.otherskeletal mass index
dc.subject.othermuscle mass
dc.subject.otherintraoperative CT scan
dc.subject.otherdistal radius fracture
dc.subject.otherO-arm radius fracture
dc.subject.otherintraoperative CT scan in trauma
dc.subject.otherDHEA
dc.subject.othersteroids
dc.subject.othercatecholamine
dc.subject.otherhealth service research
dc.subject.othermanagement of major trauma
dc.subject.othergeriatric major trauma
dc.subject.otheroutcome research
dc.subject.otherpatient-reported outcome
dc.subject.otherPolytrauma
dc.subject.otherflail chest
dc.subject.otherthoracic injury
dc.subject.otherpubic ramus fractures
dc.subject.otherfragility fractures of the pelvis
dc.subject.otherliving condition
dc.subject.othermobility
dc.subject.otherquality of life
dc.subject.othertrauma resuscitation unit
dc.subject.otheremergency medicine
dc.subject.otherinjury severity
dc.subject.otherabbreviated injury scale
dc.subject.otherinjury severity score
dc.subject.otherpelvic fracture
dc.subject.otherfragility fractures
dc.subject.otherpelvic ring
dc.subject.otherpelvic ring fracture
dc.subject.otherinsole-force sensors
dc.subject.otherweight-bearing
dc.subject.othergeriatric fracture
dc.subject.othercervical artery dissection
dc.subject.othervertebral artery
dc.subject.othercarotid artery
dc.subject.otherseverely injured
dc.subject.othercomputed tomography
dc.subject.othersacroiliac-screw
dc.subject.otherSI-screw
dc.subject.otherpercutaneous operation
dc.subject.otheraugmentation
dc.subject.otherfragility fracture
dc.subject.other3-D navigation
dc.subject.otherairway management
dc.subject.otherintubation
dc.subject.otherlaryngoscopy
dc.subject.othervideo
dc.subject.otherprehospital care
dc.subject.otherrescue helicopter
dc.subject.otherair ambulance
dc.subject.otherchest trauma
dc.subject.otherweight disorders
dc.subject.otheroverweight
dc.subject.otherobesity
dc.subject.otheroutcome
dc.subject.otherthoracoabdominal aortic aneurysm
dc.subject.otherribonuclease
dc.subject.otherribonuclease inhibitor 1
dc.subject.othercomplex aortic surgery
dc.subject.otheracute kidney injury
dc.subject.othern/a
dc.titleNew Diagnostic and Therapeutic Approaches for the Care of the Severely Injured Patient
dc.typebook
oapen.identifier.doi10.3390/books978-3-03943-778-8
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039437771
oapen.relation.isbn9783039437788
oapen.pages318
oapen.place.publicationBasel, Switzerland


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