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dc.contributor.editorDorst, Johannes
dc.date.accessioned2021-05-01T15:48:00Z
dc.date.available2021-05-01T15:48:00Z
dc.date.issued2020
dc.identifierONIX_20210501_9783039435852_1113
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/69367
dc.description.abstractApheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients’ blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain–Barré syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::M Medicine and Nursingen_US
dc.subject.otherimmunoadsorption
dc.subject.otheracute relapsing multiple sclerosis
dc.subject.otherplasma exchange
dc.subject.othertherapeutic apheresis
dc.subject.othermultiple sclerosis
dc.subject.otheroptic neuritis
dc.subject.otherrelapse
dc.subject.otherclass IV
dc.subject.othersteroids
dc.subject.otherAlzheimer’s clinical syndrome
dc.subject.otherdementia
dc.subject.otherautoantibodies
dc.subject.otherα1-Adrenergic receptor
dc.subject.otherInflammatory neuropathy
dc.subject.otherchronic inflammatory demyelinating polyneuropathy
dc.subject.otherGuillain-Barré syndrome
dc.subject.otherparanodal antibodies
dc.subject.otherplasmapheresis
dc.subject.otherMyalgic Encephalomyelitis/Chronic Fatigue Syndrome
dc.subject.otherß2 adrenoreceptor autoantibody
dc.subject.otherautoimmune encephalitis
dc.subject.otherlimbic encephalitis
dc.subject.otherNMDAR (N-Methyl-D-Aspartat)
dc.subject.otherantibody
dc.subject.otherparaneoplastic
dc.subject.otherapheresis
dc.subject.othertherapeutic plasma exchange
dc.subject.otherneurological diseases
dc.subject.otherCRP
dc.subject.otherstroke
dc.subject.otherinflammation
dc.subject.othern/a
dc.titleApheresis in Neurological Disorders
dc.typebook
oapen.identifier.doi10.3390/books978-3-03943-586-9
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039435852
oapen.relation.isbn9783039435869
oapen.pages174
oapen.place.publicationBasel, Switzerland


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