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dc.contributor.editorDavid, Robert
dc.date.accessioned2021-05-01T15:42:17Z
dc.date.available2021-05-01T15:42:17Z
dc.date.issued2020
dc.identifierONIX_20210501_9783039431922_898
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/69152
dc.description.abstractEven today, cardiovascular diseases are the main cause of death worldwide, and therapeutic approaches are very restricted. Due to the limited regenerative capabilities of terminally differentiated cardiomyocytes post injury, new strategies to treat cardiac patients are urgently needed. Post myocardial injury, resident fibroblasts begin to generate the extracellular matrix, resulting in fibrosis, and finally, cardiac failure. Recently, preclinical investigations and clinical trials raised hope in stem cell-based approaches, to be an effective therapy option for these diseases. So far, several types of stem cells have been identified to be promising candidates to be applied for treatment: cardiac progenitor cells, bone marrow derived stem cells, embryonic and induced pluripotent stem cells, as well as their descendants. Furthermore, the innovative techniques of direct cardiac reprogramming of cells offered promising options for cardiovascular research, in vitro and in vivo. Hereby, the investigation of underlying and associated mechanisms triggering the therapeutic effects of stem cell application is of particular importance to improve approaches for heart patients. This Special Issue of Cells provides the latest update in the rapidly developing field of regenerative medicine in cardiology.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
dc.subject.otherFabry disease
dc.subject.otherhuman embryonic stem cells
dc.subject.otherCRISPR/Cas9 genomic editing
dc.subject.otherMass spectrometry proteomic analysis
dc.subject.otherhypertrophic cardiomyopathy
dc.subject.otherdisease model
dc.subject.otherphysical exercise
dc.subject.othercardiac cellular regeneration
dc.subject.othermicroRNA (miR)
dc.subject.otherAkt signaling
dc.subject.othercardiomyocyte proliferation
dc.subject.othercardiac hypertrophy
dc.subject.othercardioprotection
dc.subject.othermyocarditis
dc.subject.otherinflammation
dc.subject.otherleukocytes
dc.subject.othercardiomyocytes
dc.subject.othermulti-electrode-array
dc.subject.othermicro-electrode-array
dc.subject.otherMEA
dc.subject.otherdrug/toxicity screening
dc.subject.otherfield potential
dc.subject.otherarrhythmia
dc.subject.otherelectrocardiography
dc.subject.othercardiac regeneration
dc.subject.otherstem cells
dc.subject.otheriPSC
dc.subject.otherPSC
dc.subject.otherESC
dc.subject.othercardiovascular disease
dc.subject.otherregeneration
dc.subject.othercardiac progenitor cells
dc.subject.otherinduced pluripotent stem cells
dc.subject.othertransdifferentiation
dc.subject.otherdirect reprogramming
dc.subject.othergenetic engineering
dc.subject.othercardiac tissue engineering
dc.subject.otherbiomaterials
dc.subject.other18F-FDG PET
dc.subject.othercardiac induced cells
dc.subject.othercardiac function
dc.subject.othernon-invasive imaging
dc.subject.otherhuman pluripotent stem cell
dc.subject.otherventricular
dc.subject.othermaturation
dc.subject.otherbone marrow stem cells
dc.subject.otherangiogenesis
dc.subject.othermyocardial infarction
dc.subject.otherhuman induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
dc.subject.otheriPS cells
dc.subject.otherbig conductance calcium activated potassium channel (BK)
dc.subject.otherMaxi-K
dc.subject.otherslo1
dc.subject.otherKCa1.1
dc.subject.otheriberiotoxin
dc.subject.otherlong QT syndrome
dc.subject.othermesenchymal stromal cells (MSC)
dc.subject.othermRNA
dc.subject.othermiRNA
dc.subject.othercardiac reprogramming
dc.subject.othercardiac differentiation
dc.subject.othercardiovascular diseases
dc.subject.otheradult stem cells
dc.subject.othermyocardial infraction
dc.subject.other3D printing
dc.subject.other3D model
dc.subject.otherbioprinting
dc.subject.othercardiovascular medicine
dc.subject.otherheart
dc.subject.othermyocardium
dc.subject.otherheart valves
dc.subject.othervascular graft
dc.subject.otherendothelialization
dc.subject.othertissue engineering
dc.subject.otherdecorin
dc.subject.otherfibronectin
dc.subject.otherelectrospinning
dc.subject.otherendothelial progenitor cells
dc.subject.otherbioreactor
dc.subject.otherbiostable polyurethane
dc.subject.otherMicroRNA
dc.subject.otherMir-133
dc.subject.othercoronary heart disease
dc.subject.otherbiomarker
dc.subject.othermeta-analysis
dc.titleStem Cell Research on Cardiology
dc.typebook
oapen.identifier.doi10.3390/books978-3-03943-193-9
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039431922
oapen.relation.isbn9783039431939
oapen.pages356
oapen.place.publicationBasel, Switzerland


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