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dc.contributor.editorDalton, Colin
dc.contributor.editorSalari, Alinaghi
dc.date.accessioned2021-05-01T15:41:52Z
dc.date.available2021-05-01T15:41:52Z
dc.date.issued2020
dc.identifierONIX_20210501_9783039431748_879
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/69133
dc.description.abstractMicroelectrode arrays are increasingly used in a wide variety of situations in the medical device sector. For example, one major challenge in microfluidic devices is the manipulation of fluids and droplets effectively at such scales. Due to the laminar flow regime (i.e., low Reynolds number) in microfluidic devices, the mixing of species is also difficult, and unless an active mixing strategy is employed, passive diffusion is the only mechanism that causes the fluid to mix. For many applications, diffusion is considered too slow, and thus many active pumping and mixing strategies have been employed using electrokinetic methods, which utilize a variety of simple and complex microelectrode array structures. Microelectrodes have also been implemented in in vitro intracellular delivery platforms to conduct cell electroporation on chip, where a highly localized electric field on the scale of a single cell is generated to enhance the uptake of extracellular material. In addition, microelectrode arrays are utilized in different microfluidic biosensing modalities, where a higher sensitivity, selectivity, and limit-of-detection are desired. Carbon nanotube microelectrode arrays are used for DNA detection, multi-electrode array chips are used for drug discovery, and there has been an explosion of research into brain–machine interfaces, fueled by microfabricated electrode arrays, both planar and three-dimensional. The advantages associated with microelectrode arrays include small size, the ability to manufacture repeatedly and reliably tens to thousands of micro-electrodes on both rigid and flexible substrates, and their utility for both in vitro and in vivo applications. To realize their full potential, there is a need to develop and integrate microelectrode arrays to form useful medical device systems. As the field of microelectrode array research is wide, and touches many application areas, it is often difficult to locate a single source of relevant information. This Special Issue seeks to showcase research papers, short communications, and review articles, that focus on the application of microelectrode arrays in the medical device sector. Particular interest will be paid to innovative application areas that can improve existing medical devices, such as for neuromodulation and real world lab-on-a-chip applications.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
dc.subject.otherelectrothermal
dc.subject.othermicroelectrode
dc.subject.othermicrofluidics
dc.subject.othermicromixing
dc.subject.othermicropump
dc.subject.otheralternating current (AC) electrokinetics
dc.subject.otherbisphenol A
dc.subject.otherself-assembly
dc.subject.otherbiosensor
dc.subject.otherflexible electrode
dc.subject.otherpolydimethylsiloxane (PDMS)
dc.subject.otherpyramid array micro-structures
dc.subject.otherlow contact impedance
dc.subject.othermultimodal laser micromachining
dc.subject.otherablation characteristics
dc.subject.othershadow mask
dc.subject.otherinterdigitated electrodes
dc.subject.othersoft sensors
dc.subject.otherliquid metal
dc.subject.otherfabrication
dc.subject.otherprinciple
dc.subject.otherarrays
dc.subject.otherapplication
dc.subject.otherinduced-charge electrokinetic phenomenon
dc.subject.otherego-dielectrophoresis
dc.subject.othermobile electrode
dc.subject.otherJanus microsphere
dc.subject.othercontinuous biomolecule collection
dc.subject.otherelectroconvection
dc.subject.othermicroelectrode array (MEA)
dc.subject.otherion beam assisted electron beam deposition (IBAD)
dc.subject.otherindium tin oxide (ITO)
dc.subject.othertitanium nitride (TiN)
dc.subject.otherneurons
dc.subject.othertransparent
dc.subject.otherislets of Langerhans
dc.subject.otherinsulin secretion
dc.subject.otherglucose stimulated insulin response
dc.subject.otherelectrochemical transduction
dc.subject.otherintracortical microelectrode arrays
dc.subject.othershape memory polymer
dc.subject.othersoftening
dc.subject.otherrobust
dc.subject.otherbrain tissue oxygen
dc.subject.otherin vivo monitoring
dc.subject.othermulti-site clinical depth electrode
dc.subject.othern/a
dc.titleMicroelectrode Arrays and Application to Medical Devices
dc.typebook
oapen.identifier.doi10.3390/books978-3-03943-175-5
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039431748
oapen.relation.isbn9783039431755
oapen.pages188
oapen.place.publicationBasel, Switzerland


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