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dc.contributor.editorKwok, Hang Fai
dc.date.accessioned2021-05-01T15:11:51Z
dc.date.available2021-05-01T15:11:51Z
dc.date.issued2021
dc.identifierONIX_20210501_9783036503868_266
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/68520
dc.description.abstractNatural-based biomolecules continuously play an important role in novel drug discovery for the treatment of chronic diseases. The development of natural peptide/protein-based, toxin-based, and antibody-based drugs can significantly improve the biomedical efficiency of disease-specific therapy. The focus of this Special Issue of Biomolecules will be on the most recent advances related to novel peptides/proteins, antibodies, and toxins as forms of medicinal therapy. Recent advances in the discovery and development of these natural biomolecules for use in targeted therapy and immunotherapy against chronic diseases (e.g., cancer, diabetes, cardiovascular diseases, and rheumatoid arthritis) will be addressed. The discussion on using novel disease-specific proteins/peptides/toxins/antibodies along with currently available FDA-approved drugs as combinatorial treatments will also be encouraged in this context. Finally, an overview of some of the selected promising natural biomolecules that are potentially able to address the forthcoming challenges in this field will be included. Both research (in particular) and review articles proposing novelties or overviews, respectively, are welcome.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::H Humanities
dc.subject.classificationbic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFP Social interaction
dc.subject.otherDAPK1
dc.subject.otherSUMO
dc.subject.otherSENP
dc.subject.otherprotein degradation
dc.subject.otherpost-translational modification
dc.subject.otheramphibian Bowman-Birk inhibitor
dc.subject.otherTat peptide
dc.subject.othermolecular cloning
dc.subject.otherantifungal
dc.subject.otherdrug design
dc.subject.otherprotease inhibitor
dc.subject.othernatural-based compound
dc.subject.otheranticancer therapy
dc.subject.otherlung cancer
dc.subject.othersurvivin
dc.subject.otherapoptosis
dc.subject.otherSTAT3
dc.subject.othercolorectal cancer
dc.subject.otherorientin
dc.subject.othercell cycle arrest
dc.subject.otherBcl-2 family proteins
dc.subject.otherAstragalus membranaceus
dc.subject.otherinsulin
dc.subject.otherPI3K
dc.subject.otherAKT
dc.subject.otherPPARγ
dc.subject.otherPDX-1
dc.subject.otherPetasites japonicus
dc.subject.otherAsteraceae
dc.subject.otherlignan
dc.subject.otheranti-inflammation
dc.subject.otherNO
dc.subject.otherPGE2
dc.subject.otheriNOS
dc.subject.otherCOX-2
dc.subject.othermolecular docking
dc.subject.otherpeptides
dc.subject.otherkynurenines
dc.subject.otherbinding affinity
dc.subject.otherμ-opioid receptor
dc.subject.otherpharmacophore
dc.subject.otherG-protein activation
dc.subject.otherfucoidan
dc.subject.otherPLGA
dc.subject.otherdocetaxel
dc.subject.otherdrug delivery system
dc.subject.otheranticancer therapy/cancer treatment
dc.subject.otherhIAPP
dc.subject.otheramyloidogenesis
dc.subject.otherinsulin granules
dc.subject.otherendoplasmic reticulum
dc.subject.otheranionic lipids
dc.subject.otherF23R variant
dc.subject.otherβ-sheet transitions
dc.subject.otherβ-cell cytotoxicity
dc.subject.otherunfolded protein response
dc.subject.otherpomegranate
dc.subject.otherpunicalagin
dc.subject.othertannins
dc.subject.othergingiva
dc.subject.otherfibroblasts
dc.subject.otherantioxidant
dc.subject.otherwound healing
dc.subject.otherbranched-chain fatty acids
dc.subject.otherConidiobolus heterosporus
dc.subject.otherperoxisome proliferator-activated receptor α
dc.subject.otherlipid metabolism
dc.subject.otherfatty acid oxidation
dc.subject.otherhepatocyte
dc.subject.othern/a
dc.titleNovel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
dc.typebook
oapen.identifier.doi10.3390/books978-3-0365-0387-5
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783036503868
oapen.relation.isbn9783036503875
oapen.pages180
oapen.place.publicationBasel, Switzerland


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