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dc.contributor.editorYlostalo, Joni H.
dc.date.accessioned2021-05-01T15:06:02Z
dc.date.available2021-05-01T15:06:02Z
dc.date.issued2021
dc.identifierONIX_20210501_9783039438037_23
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/68280
dc.description.abstractRecently, stem cells have been drawing increasing interest in basic and translational research that aims to understand stem cell biology and generate new therapies for various disorders. Many stem cells can be cultured in 2D relatively easily using tissue culture plastic. However, many of these cultures do not represent the natural conditions of stem cells in the body. In the body, microenvironments include numerous supporting cells and molecules. Therefore, researchers and clinicians have sought ideal stem cell preparations for basic research and clinical applications, which may be attainable through 3D culture of stem cells. The 3D cultures mimic the conditions of the natural environment of stem cells better, as cells in 3D cultures exhibit many unique and desirable characteristics that could be beneficial for therapeutic interventions. 3D stem cell cultures may employ supporting structures, such as various matrices or scaffolds, in addition to stem cells, to support complex structures. This book brings together recent research on 3D cultures of various stem cells to increase the basic understanding of stem cell culture techniques and also to highlight stem cell preparations for possible novel therapeutic applications.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
dc.subject.otherhematopoiesis
dc.subject.otherhematopoietic stem cells
dc.subject.otherstem cell culture
dc.subject.other2D culture
dc.subject.other3D culture
dc.subject.otherembryonic stem cells
dc.subject.otherthree-dimensional
dc.subject.otherself-assembling scaffold
dc.subject.otherpluripotency
dc.subject.otherculture conditions
dc.subject.otherexpansion
dc.subject.othergrowth
dc.subject.otherniche
dc.subject.otherhuman cortical progenitors
dc.subject.othersilicon pillars
dc.subject.othercell growth
dc.subject.otherhiPSC-derived neural progenitors
dc.subject.othercerebral cortex
dc.subject.othercarcinogen
dc.subject.otherprotein phosphatase 2A (PP2A)
dc.subject.otherintestinal tumor
dc.subject.otherintestinal organoid
dc.subject.otherLgr5+ crypt stem cell
dc.subject.othermouse embryonic stem cell
dc.subject.otherdifferentiation protocol
dc.subject.otherureteric bud progenitor cells
dc.subject.other3D kidney organoids
dc.subject.otherintestinal organoids
dc.subject.othercanine intestine
dc.subject.otherdifferentiation
dc.subject.otherorganoid culture
dc.subject.otherinduced pluripotent stem cells
dc.subject.otherneurospheres
dc.subject.otherneurite outgrowth
dc.subject.otherneurotoxicity
dc.subject.otherhBM-MSCs
dc.subject.othercytokines
dc.subject.othertenogenic markers
dc.subject.othercyclic strain
dc.subject.other3D microenvironment
dc.subject.otherPLGA carriers
dc.subject.otherbioreactor
dc.subject.othercardiac microtissues
dc.subject.otheriPSC-derived cardiomyocytes
dc.subject.othercardiac fibroblasts
dc.subject.othercardiac fibrosis
dc.subject.othercardiac rhythm
dc.subject.otherTGF-β signalling
dc.subject.otherdrug screening
dc.subject.otherin vitro model
dc.subject.otherstem cell
dc.subject.other3D
dc.subject.otherculture condition
dc.subject.otherregenerative medicine
dc.subject.otherscaffold
dc.subject.otherorganoid
dc.subject.otheradipose tissue-derived mesenchymal stem cells
dc.subject.otherstromal vascular fraction
dc.subject.otherplatelet rich plasma
dc.subject.otherplatelet concentrates
dc.subject.otherveterinary regenerative medicine
dc.title3D Stem Cell Culture
dc.typebook
oapen.identifier.doi10.3390/books978-3-03943-804-4
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0
oapen.relation.isbn9783039438037
oapen.relation.isbn9783039438044
oapen.pages186
oapen.place.publicationBasel, Switzerland


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