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dc.contributor.editorBiyani, Manish
dc.date.accessioned2021-04-20T15:37:39Z
dc.date.available2021-04-20T15:37:39Z
dc.date.issued2012
dc.identifierONIX_20210420_9789535108030_1597
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/66239
dc.description.abstractThe Nobel Prize in Medicine 1968 for interpretation of the genetic code and its function in protein synthesis and in Chemistry 2009 for studies of the structure and function of the ribosome highlighted the ground-breaking experiment performed on May 15, 1961 by Nirenberg and Matthaei and their principal breakthrough on the creation of "cell-free protein synthesis (CFPS) system". Since then the continuous technical advances have revitalized CFPS system as a simple and powerful technology platform for industrial and high-throughput protein production. CFPS yields exceed grams protein per liter reaction volume and offer several advantages including the ability to easily manipulate the reaction components and conditions to favor protein synthesis, decreased sensitivity to product toxicity, batch reactions last for multiple hours, costs have been reduced orders of magnitude, and suitability for miniaturization and high-throughput applications. With these advantages, there is continuous increasing interest in CFPS system among biotechnologists, molecular biologists and medical or pharmacologists.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::M Medicine::MB Medicine: general issues::MBX History of medicineen_US
dc.subject.otherCytology
dc.titleCell-Free Protein Synthesis
dc.typebook
oapen.identifier.doi10.5772/2955
oapen.relation.isPublishedBy78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6
oapen.relation.isbn9789535108030
oapen.relation.isbn9789535153283
oapen.imprintIntechOpen
oapen.pages146


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