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dc.contributor.editorMishra, Rajnikant
dc.date.accessioned2021-04-20T15:36:00Z
dc.date.available2021-04-20T15:36:00Z
dc.date.issued2012
dc.identifierONIX_20210420_9789535107071_1532
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/66174
dc.description.abstractThe complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable experimental models (microorganism, plants or animals) for testing spontaneous and induced mutations which are useful for basic and translational research. It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. It also describes mutagenesis induced by DNA damage. It has also provided advantage of in vitro transcription and translation to yield proteins with point mutations, deletions or insertions for studying stability, DNA-protein or protein-protein interaction. Trust, it will serve readers as valuable integrated resources emphasizing methods of mutagenesis, and understanding mechanism of variable penetrance or expressivity of mutations.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::T Technology, engineering, agriculture::TC Biochemical engineering::TCB Biotechnologyen_US
dc.subject.otherGenetic engineering
dc.titleMutagenesis
dc.typebook
oapen.identifier.doi10.5772/2937
oapen.relation.isPublishedBy78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6
oapen.relation.isbn9789535107071
oapen.relation.isbn9789535153122
oapen.imprintIntechOpen
oapen.pages258


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