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dc.contributor.editorLunevicius, Raimundas
dc.date.accessioned2021-04-20T15:32:50Z
dc.date.available2021-04-20T15:32:50Z
dc.date.issued2012
dc.identifierONIX_20210420_9789535105800_1410
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/66052
dc.description.abstractAlmost 30 years have gone by since the postulation that GISTs derive from mesenchymal stem elements, and only 15 years have gone by since the definitive detection of origin of GISTs. Research in the last decade was more focused upon the justification of imatinib mezylate therapy in GISTs and clarification why a secondary resistance that occurred during the kinase inhibitors therapy. The era of therapy for GISTs, targeting the primary activating mutations in the KIT proto-oncogene; is being proclaimed as bringing the message of special importance to the pathologist role in multidisciplinary team that are responsible for treating patients with locally advanced or metastatic GIST. This is the first conclusive message forthcoming from this book. On the other hand, the book provides summarised and case-based knowledge on current management of gastrointestinal and extragastrointestinal stromal tumours. We hope that this book may be considered as a worthwhile timely addition to clinical science dissemination, medical education, further basic and clinical research.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncologyen_US
dc.subject.otherOncology
dc.titleGastrointestinal Stromal Tumor
dc.typebook
oapen.identifier.doi10.5772/1892
oapen.relation.isPublishedBy78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6
oapen.relation.isbn9789535105800
oapen.relation.isbn9789535169871
oapen.imprintIntechOpen
oapen.pages132


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