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dc.contributor.authorMartinez-Sobrido, Luis*
dc.contributor.authorAlmazan Toral, Fernando*
dc.date.accessioned2021-02-11T20:53:16Z
dc.date.available2021-02-11T20:53:16Z
dc.date.issued2019*
dc.date.submitted2019-04-05 10:34:31*
dc.identifier32840*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/54549
dc.description.abstractZika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.*
dc.languageEnglish*
dc.subjectR5-920*
dc.subjectRC955-962*
dc.subject.othermicroRNAs*
dc.subject.otherantivirals*
dc.subject.otherreverse genetics*
dc.subject.othernucleic acid computation*
dc.subject.otherviral pathogenesis*
dc.subject.otherplaque reduction neutralization test*
dc.subject.otherclinical trials*
dc.subject.otherviral genetic variation*
dc.subject.otherviral fitness*
dc.subject.otherpregnancy*
dc.subject.othertype I IFN antagonist*
dc.subject.otherprM-E proteins*
dc.subject.othereye*
dc.subject.otherreplicon*
dc.subject.otherantiviral responses*
dc.subject.otherBacterial artificial chromosome*
dc.subject.othergene expression*
dc.subject.otherNS1 protein*
dc.subject.otherviral permissiveness*
dc.subject.otherZIKV–host interactions*
dc.subject.otherreporter virus*
dc.subject.otherviral persistence*
dc.subject.otherblood-retinal barrier*
dc.subject.othervirus like particles*
dc.subject.otheremerging arbovirus*
dc.subject.otherNon-human primates*
dc.subject.otherheme-oxygenase 1*
dc.subject.othermosquito surveillance*
dc.subject.otherantiviral compounds*
dc.subject.otherZIKV-associated neurologic disorders*
dc.subject.otherexternal quality assessment*
dc.subject.otheroutbreak control*
dc.subject.othertherapeutics*
dc.subject.othercryptic promoter silencing*
dc.subject.othertestis*
dc.subject.otherneurons*
dc.subject.othermutagenesis*
dc.subject.otherRNA-seq*
dc.subject.othermicrosphere immunoassay*
dc.subject.otherhost-directed antivirals*
dc.subject.othermolecular diagnostics*
dc.subject.otherBayesian analyses*
dc.subject.otherastrocytomas*
dc.subject.otherFull-length cDNA infectious clones*
dc.subject.otherviral pathogenicity*
dc.subject.otherneural progenitor cells*
dc.subject.otherfull-length molecular clone*
dc.subject.otherantiviral*
dc.subject.othermultiplex nucleic acid detection*
dc.subject.otherAsian-lineage*
dc.subject.othernucleic acid strand exchange*
dc.subject.otherIgA*
dc.subject.otherAfrican-lineage*
dc.subject.othervaccines*
dc.subject.otherZika*
dc.subject.otherresearch models and tools*
dc.subject.otherimmune response*
dc.subject.otherIgG avidity tests*
dc.subject.otherpolymerase chain reaction*
dc.subject.otherAsian lineage*
dc.subject.othersexual transmission*
dc.subject.otherTLR7/8*
dc.subject.otherneuropathogenesis*
dc.subject.othercross-reactions*
dc.subject.othergenetic variability*
dc.subject.othermosquito*
dc.subject.otherZIKV*
dc.subject.otherinfectious cDNA*
dc.subject.otherprostate*
dc.subject.otherhost genetic variation*
dc.subject.othermonoclonal antibodies*
dc.subject.otheroptimised*
dc.subject.otheranti-viral immunity*
dc.subject.otherQCMD*
dc.subject.otherarbovirus*
dc.subject.otherFSS13025*
dc.subject.otherMR766*
dc.subject.otherNS5*
dc.subject.otherEQA*
dc.subject.othertesticular cells*
dc.subject.othervirus attachment*
dc.subject.otherflavivirus*
dc.subject.othermosquito-borne flavivirus*
dc.subject.otherdsRNA*
dc.subject.otherboolean logic-processing nucleic acid probes*
dc.subject.otherZiks virus*
dc.subject.otherviral replication*
dc.subject.otherAedes aegypti*
dc.subject.otherinfection*
dc.subject.othernatural history*
dc.subject.otherinfectious RNA*
dc.subject.otherzika virus*
dc.subject.otherchimeric viruses*
dc.subject.othersubgenomic replicon*
dc.subject.otherreplication*
dc.subject.otherhuman brain glial cells*
dc.subject.othermicroglia cells*
dc.subject.otherhepatocytes*
dc.subject.otherbacterial artificial chromosome*
dc.subject.otherdetoxification and immune system responses*
dc.subject.othertestes*
dc.subject.otherdengue viruses*
dc.subject.otherZika virus*
dc.subject.otherinsecticide resistance*
dc.subject.otherNS2A protein*
dc.subject.otherplasmid toxicity*
dc.subject.othercell surface receptors*
dc.subject.otherserology*
dc.subject.otherviral evolution*
dc.subject.otherlaboratory preparedness*
dc.subject.otherflaviviruses*
dc.subject.otherTet-inducible*
dc.subject.otherdengue virus*
dc.subject.otherdiagnosis*
dc.subject.otherassay standardization*
dc.subject.otherinfectious clone*
dc.subject.otherELISA*
dc.subject.otherinnate response*
dc.subject.othercongenital Zika syndrome*
dc.subject.othersecondary infections*
dc.subject.otherapoptosis*
dc.subject.otherviral survival*
dc.subject.otherocular*
dc.subject.othervalidated*
dc.subject.otherrhesus macaques*
dc.subject.otherneuroinflammation*
dc.subject.otherplacenta cells*
dc.subject.otherNHP*
dc.subject.otherZika virus (ZIKV)*
dc.subject.otherpoint-of-care diagnostics*
dc.subject.otherisothermal nucleic acid amplification*
dc.subject.othermicrocephaly*
dc.subject.othercytopathic effects*
dc.subject.otherindirect immunofluorescence*
dc.subject.otherfetal infection*
dc.subject.othertherapy*
dc.subject.othersiRNA*
dc.subject.otherviral counteraction*
dc.subject.otherneural cells*
dc.subject.othersilvestrol*
dc.subject.othereIF4A*
dc.titleNew Advances on Zika Virus Research*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03897-765-0*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
virtual.oapen_relation_isPublishedBy.publisher_nameMDPI - Multidisciplinary Digital Publishing Institute
virtual.oapen_relation_isPublishedBy.publisher_websitewww.mdpi.com/books
oapen.relation.isbn9783038977643*
oapen.pages552*
oapen.edition1st*


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