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dc.contributor.authorRyou-u Takahashi (Ed.)*
dc.contributor.authorTakahiro Ochiya (Ed.)*
dc.date.accessioned2021-02-11T19:35:56Z
dc.date.available2021-02-11T19:35:56Z
dc.date.issued2018*
dc.date.submitted2018-10-16 10:23:45*
dc.identifier29130*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/53438
dc.description.abstractMicroRNAs (miRNAs) constitute a large family of small, approximately 20–22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostasis and that aberrant expression levels of miRNAs are involved in the onset of many diseases, including cancer. In various types of cancer, miRNAs play important roles in tumor initiation and development. Recently, miRNAs have been demonstrated to also be secreted via small endosome-derived vesicles called exosomes—which are derived from multiple cell types—including immunocytes and cancer cells. Exosomal miRNAs exert important functions in cell-to-cell communication and have been investigated as prognostic and diagnostic biomarkers.*
dc.languageEnglish*
dc.subjectR5-920*
dc.subjectRM1-950*
dc.subjectRC254-282*
dc.subject.othertumor initiation and development*
dc.subject.othercancer therapy*
dc.subject.othercirculating microRNA*
dc.subject.othermicroRNA*
dc.subject.otherdiagnosis*
dc.subject.otherbiomarker*
dc.subject.otherexosome*
dc.titleMicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03897-253-2*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
virtual.oapen_relation_isPublishedBy.publisher_nameMDPI - Multidisciplinary Digital Publishing Institute
virtual.oapen_relation_isPublishedBy.publisher_websitewww.mdpi.com/books
oapen.relation.isbn9783038972525*
oapen.relation.isbn9783038972532*
oapen.pages272*
oapen.edition1st*


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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/