Mechanisms of antibiotic resistance
Download Url(s)
http://journal.frontiersin.org/researchtopic/942/mechanisms-of-antibiotic-resistanceAuteur
Marcelo Tolmasky
Jun Lin
Marilyn C. Roberts
Kunihiko Nishino
Lixin Zhang
Rustam I. Aminov
Language
EnglishRésumé
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Keywords
Metagenomics; Antibiotic resistance mechanisms; combination therapy; antibiotics; antibiotic resistance reservoirsWebshop link
http://www.frontiersin.org/boo ...ISBN
9782889195268Publisher
Frontiers Media SAPublisher website
www.frontiersin.orgPublication date and place
2015Series
Frontiers Research Topics,Classification
Microbiology (non-medical)