HSPs - Ambiguous Mediators of Immunity
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http://journal.frontiersin.org/researchtopic/3920/hsps---ambiguous-mediators-of-immunityAuthor(s)
Stuart Keith Calderwood
Ayesha Murshid
Thiago J. Borges
Language
EnglishAbstract
Heat shock proteins (HSPs) were discovered as polypeptides induced by stress that can be found in all kingdoms of cellular organisms. Their functions were, a first enigmatic and these proteins were thus classified by molecular weight, as in—Hsp27, Hsp70, Hsp90, Hsp110. More recently, each of these size-classified molecules has attributed a role in protein folding, and they thus came to be known, as a class, as molecular chaperones. However, the they possess properties beyond chaperoning. Indeed, their discovery in the extracellular spaces suggested roles in regulation of the immune responses.
Keywords
receptor; Heat shock proteins; Vaccine; Inflammation; ImmunityWebshop link
http://www.frontiersin.org/boo ...ISBN
9782889451524Publisher
Frontiers Media SAPublisher website
www.frontiersin.orgPublication date and place
2017Series
Frontiers Research Topics,Classification
Medicine and Nursing