Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine
Download Url(s)
https://www.frontiersin.org/research-topics/6604/current-progress-and-challenges-in-the-development-of-a-b-cell-based-hepatitis-c-virus-vaccineAuthor(s)
Thomas F. Baumert
Steven K.H. Foung
Language
EnglishAbstract
More than 70 million people worldwide are infected with hepatitis C virus, a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma world-wide. In the last decade, this cancer has emerged as the second leading cause of cancer death and the global burden is increasing by two million new infections per year, mainly due to injection drug use. An effective vaccine will be the most effective means to contain the spread of this virus worldwide. The articles in this Research Topic describe the progress that has been made towards a preventive vaccine and the challenges that still need to be overcome to ultimately achieve this goal.
Keywords
Conformational epitopes; humoral immunity; Conformational structures; neutralizing antibodies; Vaccine; Hepatitis C virus; hypervariability and flexibilityISBN
9782889457144Publisher
Frontiers Media SAPublisher website
www.frontiersin.orgPublication date and place
2019Series
Frontiers Research Topics,Classification
Medicine and Nursing