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dc.contributor.authorGianfranco Donelli (Ed.)*
dc.date.accessioned2021-02-11T09:08:05Z
dc.date.available2021-02-11T09:08:05Z
dc.date.issued2015*
dc.date.submitted2016-05-12 12:14:31*
dc.identifier19032*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/42187
dc.description.abstractMicrobial biofilms have been implicated in a large number of acute and chronic infections, as well as in the failure of antibiotic treatment, particularly in hospitalized patients. In fact, the well-known persistence in the nosocomial environment of multidrug resistant microorganisms is believed to be highly promoted by the ability of the great majority of the involved bacterial and fungal species to adhere on living or abiotic surfaces, and to grow in sessile mode, to form single- or multi-species biofilms. In these communities, microbes grow encased in a hydrated matrix of extracellular polymeric substances produced by themselves and are well protected from the host immune response and the attack of antimicrobial molecules. Thus, the establishment of microbial biofilm communities on the mucosal and soft tissues of hospitalized patients, as well as on the surfaces of indwelling devices and medical instruments, is expected to have a great influence on the success of the antibiotic therapies against most of the bugs involved in nosocomial infections, being biofilm-growing bacteria and fungi much less susceptible to antibiotics.*
dc.languageEnglish*
dc.subject.othermultidrug resistant microorganisms*
dc.subject.otherprostheses*
dc.subject.othermedical devices*
dc.subject.otherantibiotic resistance*
dc.subject.othergeneral hospitals*
dc.subject.otherlong-term care settings*
dc.subject.othermedical instruments*
dc.subject.otherbacterial biofilms*
dc.subject.othernosocomial Infections*
dc.subject.otherfungal biofilms*
dc.subject.otherhealthcare-associated infections*
dc.titleBiofilm-Based Nosocomial Infections*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03842-136-8*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
virtual.oapen_relation_isPublishedBy.publisher_nameMDPI - Multidisciplinary Digital Publishing Institute
virtual.oapen_relation_isPublishedBy.publisher_websitewww.mdpi.com/books
oapen.relation.isbn9783038421351*
oapen.relation.isbn9783038421368*
oapen.pages238*
oapen.edition1st*


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