Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery: A Themed Issue Honoring Professor Victor J. Hruby on the Occasion of His 80th Birthday

Sawyer, Tomi; Haskell-Luevano, Carrie; Mosberg, Henry

doi:10.3390/books978-3-03928-289-0

Download Url(s)

https://mdpi.com/books/pdfview/book/2089

Author(s)

Sawyer, Tomi

Haskell-Luevano, Carrie

Mosberg, Henry

Language

English

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Abstract

Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development.

URI

https://directory.doabooks.org/handle/20.500.12854/40330

Keywords

fusogenic; small molecule; cancer vaccine; peptide-drug conjugate; protein–protein interaction; anticancer peptide; tetrapeptides; drug discovery; ginkgo nuts; prostaglandin F2?; macrocyclic peptide; melanocortins; Toll-like receptor; polo-box domain; endosomolytic; structure-activity; free energy calculation; peptide; autophagy; synthetic vaccine; small antimicrobial peptides; azapeptides; classification; multifunctional ligands; cytoprotective; polycationic -amino acids; N-acetylated Pam2Cys; Pam2Cys; disulfide-rich scaffold; d-amino acid scan; VEGF165; antibiotics; hyperdisulfide; peptides; random forest; pseudosubstrate; influenza hemagglutinin; Ranalexin; ?-ginkgotide; LIR motif; bioconjugation; peptide agonist; GnRH; molecular rotor dye; sensor chip; helix-breaker; Plk1; antimicrobial activity; molecular dynamics; machine learning; melanocortin-4 receptor; kinase inhibitor; support vector machine; D-amino acid; drug screen; receptor desensitization; diabetes; opioids; selectivity; IP20; aza-amino acids; bis-benzamide scaffold; G?S signaling; chemical linker; MC4R; LHRH; ?-hairpin; androgen receptor; adjuvant; high throughput screening; receptor internalization; peptide design; ?-helix mimetics; adaptogenic; obesity; cardiovascular profile; hypoxia; programmed cell death ligand protein 1; PKA; neuropilin-1; preterm labor; ?-sheet; PKI; MC3R; myometrium contractions; amphiphilic; structure–activity relationship; peptidomimetics; combinatorial chemistry; sepsis; coactivator PELP1; OBOC; mixed-mode pharmacology; configuration; peptide permeability; triazole; stapled peptide; cysteine-rich peptides; GLP-1; RBC lysis; mixed pharmacology; therapeutic peptides; opioid; peptidomimetic; prostate cancer; alanine scan; lipidation; peptide therapeutics; cancer; pharmacophore