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dc.contributor.authorSturdy, Steve
dc.date.accessioned2021-02-10T14:51:56Z
dc.date.available2021-02-10T14:51:56Z
dc.date.issued2020
dc.identifierhttps://library.oapen.org/handle/20.500.12657/42725
dc.identifier50677*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/38089
dc.description.abstractNumerous studies describe the genetic make-up of populations living outside Europe and North America. Many of these tackle human genetic variation with the explicit aim of identifying gene variants of medical significance for the populations studied. However, the chapter points to rather different motivations, showing how recent studies documenting the genetic constitution of non-Western populations have grown out of, and serve the purposes of, efforts to identify genetic factors which influence the health of populations in Europe and North America. Analysing the past thirty-five years of medical research literature, the chapter shows how, in this context, efforts to identify genetic variants of possible significance for disease aetiology have shifted to include large-scale association studies in populations rather than families. It discusses how research with local concerns must nonetheless take into account the global distribution of genes and genotypes, thus making studies of the genetic causes of disease, wherever conducted, increasingly global in their purview. The chapter also argues that this recent knowledge of human population genomics has developed in a way which reinscribes ideas of racial difference into biomedical understanding of human populations, and creates tools for excluding supposedly non-Western populations from research oriented towards the concerns of Western institutions.
dc.languageEnglish
dc.relation.ispartofseriesSocial Histories of Medicine
dc.rightsopen access
dc.subject.classificationbic Book Industry Communication::M Medicine::MB Medicine: general issues::MBX History of medicine
dc.subject.classificationbic Book Industry Communication::P Mathematics & science
dc.subject.classificationbic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations::JPSN International institutions
dc.subject.otherhuman genetic variation
dc.subject.othernon-Western populations
dc.subject.otherdisease aetiology
dc.subject.otherassociation studies
dc.subject.otherpopulation genomics
dc.titleChapter 7 Finding the global in the local
dc.title.alternativeConstructing population in the search for disease genes
dc.typechapter
oapen.relation.isPublishedBybcb4ab08-c525-4e6c-88e5-a0cf0a175533
oapen.relation.isPartOfBookcbb30680-c114-416b-843e-8f0b95d1a6ec
oapen.relation.isFundedByd859fbd3-d884-4090-a0ec-baf821c9abfd
oapen.relation.isFundedByf6fcd900-36e2-4bc9-939e-ad820802e21f
oapen.collectionWellcome
oapen.pages29
oapen.place.publicationManchester
oapen.grant.numberWT100597MA
dc.dateSubmitted2020-10-28T09:24:03Z
dc.relationisFundedByd859fbd3-d884-4090-a0ec-baf821c9abfd


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