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dc.contributor.authorTenekedjiev, Kiril Ivanov
dc.contributor.authorNikolova, Natalia Danailova
dc.contributor.authorKolev, Krasimir
dc.contributor.authorIvanov, Kiril
dc.contributor.authorDanailova, Natalia
dc.contributor.authorKolev, Krasimir
dc.date.accessioned2021-02-10T14:19:48Z
dc.date.available2021-02-10T14:19:48Z
dc.date.issued2012
dc.identifier627382
dc.identifierhttp://library.oapen.org/handle/20.500.12657/31531
dc.identifier31822*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/34722
dc.description.abstractThe biochemical models describing complex and dynamic metabolic systems are typically multi-parametric and non-linear, thus the identification of their parameters requires nonlinear regression analysis of the experimental data. The stochastic nature of the experimental samples poses the necessity to estimate not only the values fitting best to the model, but also the distribution of the parameters, and to test statistical hypotheses about the values of these parameters. In such situations the application of analytical models for parameter distributions is totally inappropriate because their assumptions are not applicable for intrinsically non-linear regressions. That is why, Monte Carlo simulations are a powerful tool to model biochemical processes.
dc.languageEnglish
dc.rightsopen access
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
dc.subject.otherbiochemistry
dc.subject.othermonte carlo simulation
dc.subject.otherbiochemistry
dc.subject.othermonte carlo simulation
dc.subject.otherConfidence interval
dc.subject.otherConfidence region
dc.subject.otherEnzyme
dc.subject.otherEnzyme kinetics
dc.subject.otherFatty acid
dc.subject.otherPlasmin
dc.subject.otherRandom variable
dc.titleChapter 4 Applications of Monte Carlo Simulation in Modelling of Biochemical Processes
dc.typechapter
oapen.identifier.doi10.5772/14984
oapen.relation.isPublishedBy035ecc65-6737-43cf-a13a-6bdf67ce01f4
virtual.oapen_relation_isPublishedBy.publisher_nameInTechOpen
oapen.relation.isPartOfBookApplications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science
virtual.oapen_relation_isPartOfBook.dc_titleApplications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science
oapen.relation.isFundedByf6fcd900-36e2-4bc9-939e-ad820802e21f
virtual.oapen_relation_isFundedBy.grantor_nameWellcome Trust
oapen.relation.isFundedByd859fbd3-d884-4090-a0ec-baf821c9abfd
oapen.collectionWellcome
oapen.grant.number083174
dc.dateSubmitted2019-10-04 14:49:35
dc.dateSubmitted2020-04-01T13:38:50Z
dc.dateSubmitted2017-04-12 23:55
dc.dateSubmitted2019-10-04 14:49:35
dc.dateSubmitted2020-04-01T13:38:50Z
dc.dateSubmitted2017-03-01 23:55:55
dc.dateSubmitted2019-10-04 14:49:35
dc.dateSubmitted2020-04-01T13:38:50Z
dc.relationisFundedByd859fbd3-d884-4090-a0ec-baf821c9abfd
dc.chapternumber1


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