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dc.contributor.editorTettelin, Hervé
dc.contributor.editorMedini, Duccio
dc.date.accessioned2021-02-10T13:53:55Z
dc.date.available2021-02-10T13:53:55Z
dc.date.issued2020
dc.identifierONIX_20200513_9783030382810_7
dc.identifier45307*
dc.identifierhttp://library.oapen.org/handle/20.500.12657/37707
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/31839
dc.description.abstractThis open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
dc.languageEnglish
dc.rightsopen access
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAJ Evolution
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PB Mathematics::PBW Applied mathematics
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
dc.subject.classificationbic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
dc.subject.otherMicrobial Genetics and Genomics
dc.subject.otherEvolutionary Biology
dc.subject.otherGenetics and Population Dynamics
dc.subject.otherMicrobial Ecology
dc.subject.otherHuman Genetics
dc.subject.otherGenetics and Genomics
dc.subject.otherComparative genomics
dc.subject.otherMetagenomics
dc.subject.otherMicrobial Population Analysis
dc.subject.otherPangenome Profile
dc.subject.otherSupra-Genome Analysis
dc.subject.otherAdaptive Evolution
dc.subject.otherComputational Tools
dc.subject.otherBioinformatic Genomics
dc.subject.otherCore Dispensable Genome
dc.subject.otherSelection, Recombination, Composition
dc.subject.otherAcquired Resistance
dc.subject.otherBacterial Species Concept
dc.subject.otherGenomic Diversity
dc.subject.otherBacterial Ecology, Microevolution
dc.subject.otherOpen Access
dc.subject.otherPan-metagenomics
dc.subject.otherPan-microbiomics
dc.subject.otherPan-epigenome
dc.subject.otherGene Transfer
dc.subject.otherPan-phenomes
dc.subject.otherMicrobiology (non-medical)
dc.subject.otherGenetics (non-medical)
dc.subject.otherEvolution
dc.subject.otherApplied mathematics
dc.subject.otherEcological science, the Biosphere
dc.subject.otherMedical genetics
dc.titleThe Pangenome
dc.title.alternativeDiversity, Dynamics and Evolution of Genomes
dc.typebook
oapen.identifier.doi10.1007/978-3-030-38281-0
oapen.relation.isPublishedBy9fa3421d-f917-4153-b9ab-fc337c396b5a
virtual.oapen_relation_isPublishedBy.publisher_nameSpringer Nature
virtual.oapen_relation_isPublishedBy.publisher_websitehttp://www.springernature.com/oabooks
oapen.imprintSpringer
oapen.pages307
oapen.place.publicationCham
dc.dateSubmitted2020-05-13T14:21:11Z


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open access
Except where otherwise noted, this item's license is described as open access