Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives

doi:10.3390/books978-3-7258-1433-6

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https://mdpi.com/books/pdfview/book/9435

Contributor(s)

Marchesi, Nicoletta (editor)

Language

English

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Abstract

Up to one billion individuals globally may be impacted by neurological illnesses, according to recent World Health Organization (WHO) research. Medical definitions of neurological illnesses include conditions that impact not only the brain but also the spinal cord and nerves in the human body. A variety of symptoms may be brought on by structural, biochemical, or electrical anomalies in the brain, spinal cord, or other nerves. Among the most prevalent are neurodegenerative diseases like Alzheimer's and other dementias, strokes, migraines, multiple sclerosis, Parkinson's disease, amyotrophic lateral sclerosis, polyneuropathies, neurological infections, brain tumours, and conditions resulting from nervous system trauma like head injuries.

URI

https://directory.doabooks.org/handle/20.500.12854/139433

Keywords

BACE1; TSPAN3; VEGF; ISM2; ELAV; secretase; PKC; RACK1; ischemic stroke; penumbra; minocycline; HuR; RNA-binding protein; inflammation; motor test; diabetic retinopathy; neuroinflammation; ROS; ER stress; NLRP3 inflammasome; galectins; P2X7R; motor neuron disease; autonomic system; mortality; non-invasive ventilation; PEG; NIMV; vascular; cardio-vascular; ELAV/HuD; BDNF; folic acid; neurodegenerative diseases; Alzheimer’s disease; CD163; white-matter hyperintensities; mild cognitive impairment; transcriptome; oxidative stress; amyotrophic lateral sclerosis; reactive oxygen species; stroke; reperfusion treatment; miRNA; NGS; hsa-miR-9-3p; hsa-miR-9-5p; enrichment analysis; GO; KEGG; aging; blood–brain barrier; perivascular macrophage; lymphatic system; multiple sclerosis; neurodegeneration; vascular impairment; whole-body cryotherapy