Dissemination and Adoption of Comparative Effectiveness Research Findings When Findings Challenge Current Practices

Abstract

A qualitative analysis of the factors that impede the translation of comparative effectiveness research (CER) into clinical practice and those that facilitate it. Case studies of five recent CER studies are used to explore the extent to which these factors led to changes in clinical practice. The root causes for the failure of translation are synthesized, and policy options to optimize the impact of future CER are proposed.