Synthetic Biology Brings New Opportunity for Antibiotics Discovery

doi:10.3390/books978-3-0365-7260-4

Download Url(s)

https://mdpi.com/books/pdfview/book/7140

Contributor(s)

Tong, Yaojun (editor)

Deng, Zixin (editor)

Bai, Linquan (editor)

Language

English

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Abstract

We are facing a complicated public health issue in the form of global drug shortages, including antibiotics. Synthetic biology empowers the next generation of antibiotics development, bringing us into a new era.

URI

https://directory.doabooks.org/handle/20.500.12854/100047

Keywords

global regulator; milbemycins; Streptomyces bingchenggensis; SspH; actinorhodin; avermectin; ceftriaxone; hepatotoxicity; metal complexes; oxidative stress; Streptomyces; comparative transcriptome; polyether antibiotics; salinomycin; exporter genes; spectroscopic studies; antioxidant capacities; hepatic functions; cancer cells; cefotaxime; Inonotus hispidus; natural product; biological activity; medicinal fungi; phytochemicals; antimicrobial agents; biosynthetic pathway; secondary metabolites; 1-benzazepine; l-kynurenine; genome mining; biosynthesis; iterative methyltransferase; genetic dereplication; cyclodipeptide; OSMAC; cytotoxicity; Zymomonas mobilis; antibiotic resistance; ampicillin; genome editing; CRISPR−Cas12a; resistance selection markers; traditional Chinese medicine; antifungal drug; immune regulation; combination of drugs; fungal infection; n/a