TY  - BOOK
AU  - Jose Antonio Morales-Gonzalez
AU  - Eduardo Osiris Madrigal-Santillan
AU  - Angel Morales-Gonzalez
AB  - Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.
DO  - 10.5772/62743
ID  - OAPEN ID: 36628
KW  - Life Sciences
KW  - Molecular Biology
KW  - Genetics and Molecular Biology
KW  - Biochemistry
L1  - https://www.intechopen.com/books/a-master-regulator-of-oxidative-stress-the-transcription-factor-nrf2
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/52842
PB  - IntechOpen
PY  - 2016
SN  - 9789535128373
SN  - 9789535128380
TI  - A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2null
ER  - 
